• Publications
  • Influence
Cerebral blood flow changes during pilocarpine-induced status epilepticus activity in the rat hippocampus
INTRODUCTION There is a known relationship between convulsive status epilepticus (SE) and hippocampal injury. Although the precise causes of this hippocampal vulnerability remains uncertain,Expand
  • 40
  • 5
  • PDF
H magnetic resonance spectroscopy in the investigation of intractable epilepsy
We have been using proton magnetic resonance spectroscopy (1H MRS) in the investigation of adults and children with intractable epilepsy. Spectra were obtained from 2 × 2 times 2 cm cubes in theExpand
  • 113
Characterising the Origin of the Arterial Spin Labelling Signal in MRI using a Multi-Echo Acquisition Approach
Introduction Arterial spin labelling (ASL) MRI [1] is increasingly being used to measure cerebral blood flow (CBF) non-invasively with good spatial and temporal resolution. However, it suffers fromExpand
  • 2
  • PDF
The simultaneous multiple-voxel processing of MRI data using Bayesian random effects modelling
p =+ + + 01 , t ≥ 0, where q and p are integers. The full random coefficients, EDP spatiotemporal changepoint model took the form ) ), ( ( ~ ) ( e τ μ k ij k ij t N t y , ij k ij k ij t t ij κ β α μExpand
A Bayesian random effects model for enhancing resolution in diffusion MRI
i u i |, , ~ ( , / ) ≠ 2 , that is, a normal distribution with mean ( i u ) given by the average of the neighbouring voxel values, and variance i u m w / 2 , where i and j are voxel labels, 2 u w isExpand
Spatial random effects modelling of crossing fibre voxels in diffusion MRI
Markov chain Monte Carlo (MCMC) simulation, as described elsewhere 1 . Methods Diffusion-weighted images were acquired using a b-value of 1000 s mm -2 and 20 directions, with two averages. SpatialExpand