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Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity
The phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin inhibitor (mTOR) pathway is often constitutively activated in human tumor cells, providing unique opportunities forExpand
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A Dynamic Approach to the Study of Rhodoliths: A Case Study for the Northwestern Gulf of Mexico
Abstract In the northwestern Gulf of Mexico, beds of rhodoliths and unconsolidated rubble at 55–70 m depth are associated with unique offshore deep bank habitats known as salt domes or diapirs. PriorExpand
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Molecular diversity of the Caulerpa racemosa–Caulerpa peltata complex (Caulerpaceae, Bryopsidales) in New Caledonia, with new Australasian records for C. racemosa var. cylindracea
Sauvage T., Payri C., Draisma S.G.A., Prud′homme van Reine W.F., Verbruggen H., Belton G.S., Gurgel C.F.D., Gabriel D., Sherwood A.R. and Fredericq S. 2013. Molecular diversity of the CaulerpaExpand
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Taxonomic studies in the Schizymeniaceae (Nemastomatales, Rhodophyta): on the identity of Schizymenia sp. in the Azores and the generic placement of Nemastoma confusum
Gabriel D., Schils T., Parente M.I., Draisma S.G.A., Neto A.I. and Fredericq S. 2011. Taxonomic studies in the Schizymeniaceae (Nemastomatales, Rhodophyta): on the identity of Schizymenia sp. in theExpand
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Phylogenetic appraisal of the genus Platoma (Nemastomatales, Rhodophyta), including life history and morphological observations on P. cyclocolpum from the Azores
Gabriel D., Parente M.I., Neto A.I., Raposo M., Schils T. and Fredericq S. 2010. Phylogenetic appraisal of the genus Platoma (Nemastomatales, Rhodophyta), including life history and morphologicalExpand
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Comparison of Variability and Sensitivity between Nuclear Translocation and Luciferase Reporter Gene Assays
High-content screening (HCS), a technology based on subcellular imaging by automated microscopy and sophisticated image analysis, has emerged as an important platform in small-molecule screening forExpand
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An imaging assay to analyze primary neurons for cellular neurotoxicity
The development of high-content screening technologies including automated immunostaining, automated image acquisition and automated image analysis have enabled higher throughput of cellularExpand
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Image-Based High-Content Screening in Drug Discovery
TLDR
Immunofluorescence microscopy is a powerful tool for the detection of multiple changes in single cells at sub-cellular level. Expand
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MuSK myasthenia gravis and pregnancy
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