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Interactions and developmental effects of mutations in the Broad-Complex of Drosophila melanogaster.
The 2B5 region on the X chromosome of Drosophila melanogaster forms an early ecdysone puff at the end of the third larval instar. The region contains a complex genetic locus, the Broad-Complex (BR-C)Expand
Autosomal mutations affecting adhesion between wing surfaces in Drosophila melanogaster.
Integrins are evolutionarily conserved transmembrane alpha,beta heterodimeric receptors involved in cell-to-matrix and cell-to-cell adhesions. In Drosophila the position-specific (PS) integrinsExpand
The cellular basis of epithelial morphogenesis. A review.
The distribution of PS integrins, laminin A and F-actin during key stages in Drosophila wing development.
We first summarize wing development during metamorphosis of Drosophila and identify four critical steps in the conversion of a folded single layered wing disc to a flat bilayered wing. Each stepExpand
Apical cell shape changes during Drosophila imaginal leg disc elongation: a novel morphogenetic mechanism.
Imaginal discs of Drosophila are simple epithelial tissues that undergo dramatic changes in shape during metamorphosis, including elongation to form adult appendages such as legs and wings. We haveExpand
Blistered: a gene required for vein/intervein formation in wings of Drosophila.
We have characterized the blistered (bs) locus phenotypically, genetically and developmentally using a set of new bs alleles. Mutant defects range from wings with ectopic veins and intervein blistersExpand
Interaction of the Stubble-stubbloid locus and the Broad-complex of Drosophila melanogaster.
The 2B5 region on the X chromosome of Drosophila melanogaster forms an early ecdysone puff at the end of the third instar. The region is coextensive with a complex genetic locus, the Broad-ComplexExpand
The making of a fly leg: A model for epithelial morphogenesis
Epithelial development dictates the shape of an organism. The metamorphic development of a Drosophila leg precursor into an adult leg is a well‐defined example of epithelial morphogenesis that can beExpand
The mechanism of evagination of imaginal discs of Drosophila melanogaster. 1. General considerations.
Abstract Morphological and ultrastructural observations of evaginating discs are presented along with studies of the biochemical and cellular effects of inhibitors of evagination, particularlyExpand
The mechanism of evagination of imaginal discs of Drosophila melanogaster. III. Evidence for cell rearrangement.
  • D. Fristrom
  • Biology, Medicine
  • Developmental biology
  • 1 December 1976
The shape and arrangement of cells in leg discs of Drosophila melanogaster at different stages of evagination were examined by scanning electron microscopy. The observations indicate that the changeExpand
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