D. Franken

Publications11
h-index9
Citations948
Highly Influential Citations19
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Thermolabile 5,10-methylenetetrahydrofolate reductase as a cause of mild hyperhomocysteinemia.
Thermolability of 5,10-methylenetetrahydrofolate reductase (MTHFR) was examined as a possible cause of mild hyperhomocysteinemia in patients with premature vascular disease. Control subjects and… Expand
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Principles of Minimal Cognition: Casting Cognition as Sensorimotor Coordination
TLDR
We argue that minimal cognition is better explicated as a much more general biological phenomenon, allowing the lower bound of cognition to extend much further down the phylogenetic scale. Expand
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Treatment of mild hyperhomocysteinemia in vascular disease patients.
Mild hyperhomocysteinemia is recognized as a risk factor for premature arteriosclerotic disease. A few vitamins and other substances have been reported to reduce blood homocysteine levels, but… Expand
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Combined vitamin B6 plus folic acid therapy in young patients with arteriosclerosis and hyperhomocysteinemia.
PURPOSE Hyperhomocysteinemia is associated with arteriosclerotic and thromboembolic events. The homocysteine-lowering effect of combined treatment with vitamin B6 plus folic acid has never been… Expand
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Prevalence of familial mild hyperhomocysteinemia.
Previous studies have shown that elevated basal homocysteine levels are correlated among family members of patients with coronary vascular disease and juvenile venous thrombosis. This suggests the… Expand
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Thiamine (vitamin B1) supplementation does not reduce fasting blood homocysteine concentration in most homozygotes for homocystinuria.
Homozygotes for homocystinuria due to cystathionine synthase (CS) deficiency accumulate homocysteine and methionine in their blood and tissues. High-dose pyridoxin, folic acid, vitamin B12, or… Expand
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Effect of various regimens of vitamin B6 and folic acid on mild hyperhomocysteinaemia in vascular patients
Lin C-H, Hsiao K-J, Tsai T-F, Chao H-K, Su T-S (1992) Identification of a missense phenylketonuria mutation at codon 408 in Chinese. Hum Genet 89: 593-596. Okano Y, Eisensmith RC, Gfittler F et al… Expand
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Familial Cerebrovascular Accidents Due to Concomitant Hyperhomocysteinemia and Protein C Deficiency Type 1
Background and Purpose Hyperhomocysteinemia and protein C deficiency are risk factors for thromboembolism. Hyperhomocysteinemia has been reported to inhibit the expression of thrombomodulin and to… Expand
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Principles of minimal cognition
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Annual Report BCN 2004-2005: Graduate School of Behavioral and Cognitive Neurosciences