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Anti-Escherichia coli asparaginase antibody levels determine the activity of second-line treatment with pegylated E coli asparaginase: a retrospective analysis within the ALL-BFM trials.
Erwinia ASE was found to be the best ASE alternative if Ab levels against E coli ASE exceed 200 AU/mL, and in the presence of moderate or intermediate Ab levels the switch from native to pegylated E bacteria resulted in a significant increase of ASE activity above the threshold of 100 U/L.
Allergens of horse epithelium. I. Physicochemical and immunochemical characterization of five different horse epithelium raw materials used for allergen extract preparation.
- D. Franke, H. Maasch, R. Wahl, G. Schultze-Werninghaus, H. Bretting
- Biology, MedicineInternational archives of allergy and applied…
It appears that some of the differences, e.g. the content of serum-related proteins, depend on the way the different raw materials are prepared, and whole skin cannot be recommended as starting material for horse epithelial allergen extract preparation.
Evaluation of a new ELISA for the detection of specific IgG to the Epstein-Barr nuclear antigen 1 (EBNA-1).
The evaluation of the quantitative EBV EBNA-1-IgG-ELISA PKS medac was evaluated regarding its suitability for routine diagnosis and showed that the assay meets the demands of routine diagnosis very well.
Comparative pharmacokinetic/pharmacodynamic characterisation of a new pegylated recombinant E. colil-asparaginase preparation (MC0609) in Beagle dog
- S. Borghorst, G. Hempel, Sabine Poppenborg, D. Franke, T. König, J. Baumgart
- Biology, MedicineCancer Chemotherapy and Pharmacology
- 17 June 2014
The new pegylated recombinant l-asparaginase preparation MC0609 revealed striking differences in PK/PD properties compared with Oncaspar® in rat and dog.
Allergen extracts used for diagnosis and therapy: state of the art of allergen extract standardization.
HAMA-ELISA medac: a new assay for the quantitation of human anti-mouse antibodies.
Evaluation of a novel immunoglobulin a capture enzyme immunoassay for diagnosis of cytomegalovirus infection in renal and heart transplant recipients
- P. Rautenberg, L. Fischer, R. Tönnies, D. Franke
- Medicine, BiologyEuropean Journal of Clinical Microbiology and…
- 1 September 1997
The pp65 antigen assay, which detectspp65 antigen in leukocytes, is the method of choice for diagnosis of either primary or recurrent CMV infection.
162 Horse allergens: Characterization of single allergens using monoclonal antibodies
Diagnostic evaluation of a new panel of assays for Epstein-Barr virus serology.
This study was performed to evaluate the diagnostic performance of the new commercial assays EBV EBNA-1-IgG-ELISA PKS medac, EBV VCA-IhgM-ELA Test PKSMedac, and EBV EIAs using indirect immunofluorescence (IFA) as reference.