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The SLC3 and SLC7 families of amino acid transporters.
Amino acids are necessary for all living cells and organisms. Specialized transporters mediate the transfer of amino acids across plasma membranes. Malfunction of these proteins can affect whole-bodyExpand
Atomic-force microscopy: Rhodopsin dimers in native disc membranes
In vertebrate retinal photoreceptors, the rod outer-segment disc membranes contain densely packed rhodopsin molecules for optimal light absorption and subsequent amplification by the visualExpand
Organization of the G Protein-coupled Receptors Rhodopsin and Opsin in Native Membranes*
G protein-coupled receptors (GPCRs), which constitute the largest and structurally best conserved family of signaling molecules, are involved in virtually all physiological processes. CrystalExpand
Cultivation strategies to enhance productivity of Pichia pastoris: A review.
Pichia pastoris, a methylotrophic yeast, is an established system for the production of heterologous proteins, particularly biopharmaceuticals and industrial enzymes. To maximise and optimise theExpand
Molecular architecture of photosynthetic membranes in Rhodobacter sphaeroides: the role of PufX
The effects of the PufX polypeptide on membrane architecture were investigated by comparing the composition and structures of photosynthetic membranes from PufX+ and PufX− strains of RhodobacterExpand
Electrostatically balanced subnanometer imaging of biological specimens by atomic force microscope.
To achieve high-resolution topographs of native biological macromolecules in aqueous solution with the atomic force microscope (AFM) interactions between AFM tip and sample need to be considered.Expand
The supramolecular assemblies of voltage-dependent anion channels in the native membrane.
Voltage-dependent anion channels (VDACs) are major constituents of the outer mitochondrial membrane (OMM). These primary transporters of nucleotides, ions and metabolites mediate a substantialExpand
Structure of the rhodopsin dimer: a working model for G-protein-coupled receptors.
G-protein-coupled receptors (GPCRs) participate in virtually all physiological processes. They constitute the largest and most structurally conserved family of signaling molecules. Several class CExpand
The G protein‐coupled receptor rhodopsin in the native membrane
The higher‐order structure of G protein‐coupled receptors (GPCRs) in membranes may involve dimerization and formation of even larger oligomeric complexes. Here, we have investigated the organizationExpand
Imaging and manipulation of biological structures with the AFM.
Many biologists have dreamt of physically touching and manipulating the biomolecules they were investigating. With the invention of the atomic force microscope (AFM), this dream has come true. Here,Expand