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The Y chromosome pool of Jews as part of the genetic landscape of the Middle East.
A sample of 526 Y chromosomes representing six Middle Eastern populations (Ashkenazi, Sephardic, and Kurdish Jews from Israel; Muslim Kurds; Muslim Arabs from Israel and the Palestinian AuthorityExpand
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Sex identification of archaeological human remains based on amplification of the X and Y amelogenin alleles.
Sex identification of archaeological human remains is essential for the exploration of gender differences in past populations. Traditional morphometric analyses fail to identify the gender ofExpand
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Mean corpuscular volume of heterozygotes for beta-thalassemia correlates with the severity of mutations.
The relationship between the degree of microcytosis and the type of mutation carried by beta-thalassemia heterozygotes was investigated. In 113 individuals, 18 different mutations were identified,Expand
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Cost-benefit analysis of a national thalassaemia prevention programme in Israel
Objective In Israel (population 5.7 million) there are around 200 known living subjects with thalassaemia major, of whom around 80% are from the northern district. This study aims at examining theExpand
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THE β+-IVS-I-6 (T → C) MUTATION ACCOUNTS FOR HALF OF THE THALASSEMIA CHROMOSOMES IN THE PALESTINIAN POPULATIONS OF THE MOUNTAIN REGIONS
A study of the spectrum of β-thalassemia mutations in the southern part of the West Bank of the Palestinian Authority revealed the presence of 10 different β-globin mutations. The study included 41Expand
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Evolution of a genetic disease in an ethnic isolate: beta-thalassemia in the Jews of Kurdistan.
beta-Thalassemia is a hereditary disease caused by any of 90 different point mutations in the beta-globin gene. Specific populations generally carry a small number of mutations, the most common ofExpand
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Diversity of beta-globin mutations in Israeli ethnic groups reflects recent historic events.
We characterized nearly 500 beta-thalassemia genes from the Israeli population representing a variety of ethnic subgroups. We found 28 different mutations in the beta-globin gene, including threeExpand
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Sequence analysis reveals a β–thalassaemia mutation in the DNA of skeletal remains from the archaeological site of Akhziv, Israel
β–Thalassaemia is manifested by severe anaemia and extensive bone pathology. Similar pathology may also result from other forms of anaemia. To clarify the precise cause, we performed DNA analyses onExpand
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Genetic evidence for the expansion of Arabian tribes into the Southern Levant and North Africa.
To the Editor: In a recent publication, Bosch et al. (2001) reported on Y-chromosome variation in populations from northwestern (NW) Africa and the Iberian peninsula. They observed a high degreeExpand
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Determining the Sex of Infanticide Victims from the Late Roman Era through Ancient DNA Analysis
Infanticide has since time immemorial been an accepted practice for disposing of unwanted infants. Archaeological evidence for infanticide was obtained in Ashkelon, where skeletal remains of some 100Expand
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