D. Fergusson

Publications
Influence

A comparison of aprotinin and lysine analogues in high-risk cardiac surgery.

D. Fergusson, P. Hébert, +16 authors Roanda Pretorius
Medicine
The New England journal of medicine
29 May 2008

BACKGROUND Antifibrinolytic agents are commonly used during cardiac surgery to minimize bleeding and to reduce exposure to blood products. We sought to determine whether aprotinin was superior to… Expand

Detection, evaluation, and management of preoperative anaemia in the elective orthopaedic surgical patient: NATA guidelines

L. Goodnough, A. Maniatis, +10 authors M. Szpalski
Medicine
British journal of anaesthesia
1 January 2011

Previously undiagnosed anaemia is common in elective orthopaedic surgical patients and is associated with increased likelihood of blood transfusion and increased perioperative morbidity and… Expand

Clinical consequences of red cell storage in the critically ill

A. Tinmouth, D. Fergusson, I. C. Yee, P. Hébert
Medicine
Transfusion
1 November 2006

Red cell (RBC) transfusions are a potentially life‐saving therapy employed during the care of many critically ill patients to replace losses in hemoglobin to maintain oxygen delivery to vital organs.… Expand

Effect of study setting on anticoagulation control: a systematic review and metaregression.

C. van Walraven, A. Jennings, Natalie Oake, D. Fergusson, A. Forster
Medicine
Chest
1 May 2006

BACKGROUND For patients receiving therapy with oral anticoagulants (OACs), the proportion of time spent in the therapeutic range (ie, anticoagulation control) is strongly associated with bleeding and… Expand

Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.

D. Henry, P. Carless, +4 authors K. Ker
Medicine
The Cochrane database of systematic reviews
16 March 2011

BACKGROUND Concerns regarding the safety of transfused blood have led to the development of a range of interventions to minimise blood loss during major surgery. Anti-fibrinolytic drugs are widely… Expand

Prolonged therapeutic hypothermia after traumatic brain injury in adults: a systematic review.

L. McIntyre, D. Fergusson, P. Hébert, D. Moher, J. S. Hutchison
Medicine
JAMA
11 June 2003

CONTEXT The benefits of therapeutic hypothermia as a treatment for traumatic brain injury (TBI) remain unclear. OBJECTIVE To explore the effects of depth, duration, and rate of rewarming after… Expand

Association of hydroxyethyl starch administration with mortality and acute kidney injury in critically ill patients requiring volume resuscitation: a systematic review and meta-analysis.

R. Zarychanski, A. Abou-Setta, +4 authors D. Fergusson
Medicine
JAMA
20 February 2013

IMPORTANCE Hydroxyethyl starch is commonly used for volume resuscitation yet has been associated with serious adverse events, including acute kidney injury and death. Clinical trials of hydroxyethyl… Expand

Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.

D. Henry, A. Moxey, +6 authors D. Fergusson
Medicine
The Cochrane database of systematic reviews
2001

BACKGROUND Concerns regarding the safety of transfused blood have prompted re-consideration of the use of allogeneic (blood from an unrelated donor) blood transfusion. OBJECTIVES To assess the… Expand

Cell salvage for minimising perioperative allogeneic blood transfusion.

P. Carless, D. Henry, A. J. Moxey, D. O'Connell, T. Brown, D. Fergusson
Medicine
The Cochrane database of systematic reviews
14 April 2010

BACKGROUND Concerns regarding the safety of transfused blood have prompted reconsideration of the use of allogeneic (from an unrelated donor) red blood cell (RBC) transfusion, and a range of… Expand

Age of transfused blood in critically ill adults.

J. Lacroix, P. Hébert, +18 authors D. Vo
Medicine
The New England journal of medicine
8 April 2015

BACKGROUND Fresh red cells may improve outcomes in critically ill patients by enhancing oxygen delivery while minimizing the risks of toxic effects from cellular changes and the accumulation of… Expand

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