• Publications
  • Influence
A comparison of aprotinin and lysine analogues in high-risk cardiac surgery.
BACKGROUND Antifibrinolytic agents are commonly used during cardiac surgery to minimize bleeding and to reduce exposure to blood products. We sought to determine whether aprotinin was superior toExpand
  • 973
  • 35
  • PDF
Detection, evaluation, and management of preoperative anaemia in the elective orthopaedic surgical patient: NATA guidelines
Previously undiagnosed anaemia is common in elective orthopaedic surgical patients and is associated with increased likelihood of blood transfusion and increased perioperative morbidity andExpand
  • 401
  • 22
  • PDF
Clinical consequences of red cell storage in the critically ill
Red cell (RBC) transfusions are a potentially life‐saving therapy employed during the care of many critically ill patients to replace losses in hemoglobin to maintain oxygen delivery to vital organs.Expand
  • 533
  • 20
Effect of study setting on anticoagulation control: a systematic review and metaregression.
BACKGROUND For patients receiving therapy with oral anticoagulants (OACs), the proportion of time spent in the therapeutic range (ie, anticoagulation control) is strongly associated with bleeding andExpand
  • 492
  • 20
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
BACKGROUND Concerns regarding the safety of transfused blood have led to the development of a range of interventions to minimise blood loss during major surgery. Anti-fibrinolytic drugs are widelyExpand
  • 600
  • 17
  • PDF
Prolonged therapeutic hypothermia after traumatic brain injury in adults: a systematic review.
CONTEXT The benefits of therapeutic hypothermia as a treatment for traumatic brain injury (TBI) remain unclear. OBJECTIVE To explore the effects of depth, duration, and rate of rewarming afterExpand
  • 333
  • 16
  • PDF
Association of hydroxyethyl starch administration with mortality and acute kidney injury in critically ill patients requiring volume resuscitation: a systematic review and meta-analysis.
IMPORTANCE Hydroxyethyl starch is commonly used for volume resuscitation yet has been associated with serious adverse events, including acute kidney injury and death. Clinical trials of hydroxyethylExpand
  • 477
  • 15
  • PDF
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
BACKGROUND Concerns regarding the safety of transfused blood have prompted re-consideration of the use of allogeneic (blood from an unrelated donor) blood transfusion. OBJECTIVES To assess theExpand
  • 312
  • 15
  • PDF
Cell salvage for minimising perioperative allogeneic blood transfusion.
BACKGROUND Concerns regarding the safety of transfused blood have prompted reconsideration of the use of allogeneic (from an unrelated donor) red blood cell (RBC) transfusion, and a range ofExpand
  • 284
  • 15
Age of transfused blood in critically ill adults.
BACKGROUND Fresh red cells may improve outcomes in critically ill patients by enhancing oxygen delivery while minimizing the risks of toxic effects from cellular changes and the accumulation ofExpand
  • 419
  • 13
  • PDF