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- Publications
- Influence
Glycoprotein E1 of hog cholera virus expressed in insect cells protects swine from hog cholera.
- M. Hulst, D. F. Westra, G. Wensvoort, R. Moormann
- Biology, Medicine
- Journal of virology
- 1 September 1993
The processing and protective capacity of E1, an envelope glycoprotein of hog cholera virus (HCV), were investigated after expression of different versions of the protein in insect cells by using a… Expand
Induction of interferon-alpha by glycoprotein D of herpes simplex virus: a possible role of chemokine receptors.
- H. Ankel, D. F. Westra, S. Welling-Wester, P. Lebon
- Biology, Medicine
- Virology
- 25 November 1998
The induction of type I interferons by most RNA viruses is initiated by virus-derived double-stranded (ds)RNA. However, retro- and DNA-viruses, which do not synthesize dsRNA, must rely on different… Expand
Epitope mapping of inhibitory antibodies against platelet glycoprotein Ibalpha reveals interaction between the leucine-rich repeat N-terminal and C-terminal flanking domains of glycoprotein Ibalpha.
- N. Cauwenberghs, K. Vanhoorelbeke, +7 authors H. Deckmyn
- Chemistry, Medicine
- Blood
- 1 August 2001
The interaction of von Willebrand factor (vWF) with the platelet receptor glycoprotein Ibalpha (GPIbalpha) is important for platelet adhesion at high shear stress. Two functionally important… Expand
Glycoprotein H of herpes simplex virus type 1 requires glycoprotein L for transport to the surfaces of insect cells.
- D. F. Westra, K. Glazenburg, +5 authors S. Welling-Wester
- Biology, Medicine
- Journal of virology
- 1 March 1997
In mammalian cells, formation of heterooligomers consisting of the glycoproteins H and L (gH and gL) of herpes simplex virus type 1 is essential for the cell-to-cell spread of virions and for the… Expand
Effect of thiomersal on dissociation of intact (146S) foot-and-mouth disease virions into 12S particles as assessed by novel ELISAs specific for either 146S or 12S particles.
- M. Harmsen, H. Fijten, D. F. Westra, J. Coco-Martin
- Biology, Medicine
- Vaccine
- 24 March 2011
Intact (146S) foot-and-mouth disease virions (FMDVs) can dissociate into specific (12S) viral capsid degradation products. Using two single-domain antibody fragments that bind specifically to either… Expand
Immobilised metal-ion affinity chromatography purification of histidine-tagged recombinant proteins: a wash step with a low concentration of EDTA.
- D. F. Westra, G. Welling, D. G. Koedijk, A. Scheffer, T. The, S. Welling-Wester
- Chemistry, Medicine
- Journal of chromatography. B, Biomedical sciences…
- 25 August 2001
Immobilised metal-ion affinity chromatography (IMAC) is widely used for the purification of recombinant proteins in which a poly-histidine tag is introduced. However, other proteins may also bind to… Expand
Natural infection with herpes simplex virus type 1 (HSV-1) induces humoral and T cell responses to the HSV-1 glycoprotein H:L complex.
- D. F. Westra, G. Verjans, +5 authors S. Welling-Wester
- Biology, Medicine
- The Journal of general virology
- 1 August 2000
The glycoproteins of herpes simplex virus type 1 (HSV-1) are important targets for the immune system in the control of HSV-1 infections. The humoral and T cell responses to the glycoprotein… Expand
Stabilizing effects of excipients on dissociation of intact (146S) foot-and-mouth disease virions into 12S particles during storage as oil-emulsion vaccine.
- M. Harmsen, H. Fijten, D. F. Westra, A. Dekker
- Chemistry, Medicine
- Vaccine
- 15 May 2015
Most conventional foot-and-mouth disease virus (FMDV) vaccines contain oil-adjuvant. Their potency decreases upon prolonged storage. Intact (146S) FMDV particles can dissociate into 12S degradation… Expand
Domains of glycoprotein H of herpes simplex virus type 1 involved in complex formation with glycoprotein L.
- D. F. Westra, H. B. Kuiperij, G. Welling, A. Scheffer, T. The, S. Welling-Wester
- Biology, Medicine
- Virology
- 15 August 1999
The complex formation between glycoproteins H (gH) and L (gL) of herpes simplex virus type 1 (HSV-1) was studied by using five recombinant baculoviruses expressing open reading frames that contain… Expand
Characterization of glycoprotein C of HSZP strain of herpes simplex virus 1.
- I. Oravcová, M. Kúdelová, +5 authors J. Rajčáni
- Biology, Medicine
- Acta virologica
- 1 April 2000
Sequences of UL44 genes of strains HSZP, KOS and 17 of herpes simplex virus 1 (HSV-1) were determined and the amino acid sequences of corresponding glycoproteins (gC) were deduced. In comparison with… Expand