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Differential biosynthesis of prostaglandins by hydronephrotic rabbit and cat kidneys.
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D‐ AND L‐STEREOISOMERS OF ALLYLGLYCINE: CONVULSIVE ACTION AND INHIBITION OF BRAIN L‐GLUTAMATE DECARBOXYLASE
DL‐Allylglycine was resolved into the L‐ and D‐stereoisomers using hog kidney acylase. Both isomers were active as convulsants after administration to mice. The dose of D‐allylglycine required toExpand
  • 61
A novel prostaglandin 11-keto reductase found in rabbit liver.
The prostaglandin 11-keto reductase of rabbits, which catalyzes the conversion of prostaglandin D2 to prostaglandin F2 alpha, is only found in the liver. This enzyme, which is primarily localized inExpand
  • 27
INHIBITION OF BRAIN GLUTAMATE DECARBOXYLASE BY 2‐KETO‐4‐PENTENOIC ACID, A METABOLITE OF ALLYLGLYCINE 1
Abstract— 2‐Keto‐4‐pentenoic acid, a potent inhibitor of brain glutamate decarboxylase (Orlowskiet al., 1977) was prepared by oxidative deamination of l‐allylglycine with snake venom l‐amino acidExpand
  • 16
The induction of thromboxane synthetase as an expression of renal pathology
Abstract Arachidonic acid metabolism by intact perfused kidneys or by microsomes prepared from normal rabbit kidneys primarily results in the formation of prostaglandin (PG)E 2 . Unilateral ureterExpand