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An investigation on burn wound healing in rats with chitosan gel formulation containing epidermal growth factor.
Various studies have shown that chitosan is effective in promoting wound healing. In this study, we aimed to develop an effective chitosan gel formulation containing epidermal growth factor (EGF),Expand
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Development of long-acting bioadhesive vaginal gels of oxybutynin: formulation, in vitro and in vivo evaluations.
Overactive bladder (OAB) and vaginal dryness are common problems after menopause. Oxybutynin (OXY) is an antimuscarinic agent that has been available for more than 30 years in the treatment of OABExpand
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In vitro and in vivo investigations of the wound healing effect of crude Spirulina extract and C-phycocyanin
The aim of this study was to evaluate the influence of crude Spirulina extract and C-phycocyanin (C-PC) isolated from crude Spirulina extract on cultured human keratinocyte, using in vitro and inExpand
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The ultrastructural alterations in rat corneas with experimentally-induced diabetes mellitus.
OBJECTIVE To examine the ultrastructural changes of rat corneas in streptozotocin (STZ) induced diabetes mellitus and the follow-up insulin treatment. METHODS Sprague-Dawley type rats was used forExpand
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Antioxidant and triglyceride-lowering effects of vitamin E associated with the prevention of abnormalities in the reactivity and morphology of aorta from streptozotocin-diabetic rats. Antioxidants in
In this study, we evaluated the effects of vitamin E on the vascular reactivity and structure of thoracic aorta from streptozotocin (STZ)-diabetic rats. Plasma glucose, cholesterol, and triglycerideExpand
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Melatonin prevents inflammation and oxidative stress caused by abdominopelvic and total body irradiation of rat small intestine.
We investigated the day-night differences in intestinal oxidative-injury and the inflammatory response following total body (TB) or abdominopelvic (AP) irradiation, and the influence of melatoninExpand
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Histologic and morphologic effects of valproic acid and oxcarbazepine on rat uterine and ovarian cells
Purpose:  To determine the histologic and morphologic effects of valproic acid (VPA) and oxcarbazepine (OXC) on rat uterine and ovarian cells.
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Methylphenidate has dose-dependent negative effects on rat spermatogenesis: decreased round spermatids and testicular weight and increased p53 expression and apoptosis
In the present study, we aimed to evaluate the possible effects of methylphenidate on rat testes. Forty-two Wistar rats were randomly distributed into three experimental groups of 14 rats each. ForExpand
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Assessment of vascular endothelial growth factor and matrix metalloproteinase-9 in the periodontium of rats treated with atorvastatin.
BACKGROUND The aim of this study is to examine, for the first time, the role of systemic and local atorvastatin application on periodontium using histomorphometric and immunohistochemical analysisExpand
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Effect of melatonin and time of administration on irradiation-induced damage to rat testes.
The effect of ionizing irradiation on testes and the protective effects of melatonin were investigated by immunohistochemical and electron microscopic methods. Eighty-two adult male Wistar rats wereExpand
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