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[Characterization of Ca-uptake by a microsomal fraction from vascular smooth muscle].
A microsomal fraction was isolated from the media-intima of the bovine carotid artery; the preparation is a mixed fraction of membranal and mitochondrial debris, which is able to bind Ca-ions and to…
TEMPORAL RELATIONSHIP BETWEEN CARDIAC PERFORMANCE AND MYOCARDIAL UPTAKE OF DL‐PROPRANOLOL IN MAN
- B. Hesse, J. F. Hansen, E. Steiness, D. Ehlers, J. D. Andersen
- MedicineClinical and experimental pharmacology…
- 1 June 1979
1. The temporal relationship between the myocardial arteriovenous difference of plasma propranolol concentration and heart rate and left ventricular dp/dt maximum was examined for 30 min after…
[Experiments on the mechanism of action of vascular spasmolytics. 4. Effect of nitroprusside sodium, nitroglycerin, prenylamine and verapamil on the calcium uptake of microsomes of the smooth…
Nitroprusside-sodium, nitroglycerol, and verapamil had no effect on the calcium uptake by microsomes from the carotid artery of cattle. Prenylamine reduced the passive binding and the active uptake…
Side effects of the trypanocidal chemotherapeutics trypan blue and suramin.
- D. Ehlers
- Biology, ChemistryAngewandte Parasitologie
- 1 August 1989
Both the uptake of C3-opsonized and of nonopsonization bakers' yeast is inhibited by 1 mM trypan blue, and the importance of these effects for therapeutic utilization is discussed.
Myocardial A-V differences of catecholamines, lactate, free fatty acids, and O2 in ischemic heart disease after propranolol during exercise
[Participation of a phosphatase in the Ca regulation in actomyosin preparations from smooth vascular muscle].
- D. Ehlers
- BiologyActa biologica et medica Germanica
The results are related to a phosphorylation-dephosphorylation cycle to realize the Ca-sensitivity of superprecipitation of the actomyosin.
Isolation and characterization of phosphatases from vascular smooth muscle.
- D. Ehlers
- Chemistry, BiologyActa biologica et medica Germanica
Actomyosin preparations of the carotid arteries of cattle contain a soluble phosphatase activity, which can be removed from the contractile proteins by repeated washings by means of gel filtration and is characterized with respect to their inhibition by potassium fluoride, ammonium molybate, and vanadate and their dependence on pH.