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A quantitative analysis of the impact of cryopreservation on the implantation potential of human early cleavage stage embryos.
The impact of cryopreservation on the implantation potential of early cleavage stage (day 2) embryos was assessed by analysing the outcome from > 5000 thawed embryos in relation to the outcome from a… Expand
A critical appraisal of cryopreservation (slow cooling versus vitrification) of human oocytes and embryos.
BACKGROUND Vitrification is now a commonly applied technique for cryopreservation in assisted reproductive technology (ART) replacing, in many cases, conventional slow cooling methodology. This… Expand
Human oocyte cryopreservation.
The clinical role of oocyte cryopreservation in assisted reproduction, as an adjunct to sperm and embryo cryopreservation, has been comparatively slow to evolve as a consequence of theoretical… Expand
Effect of cooling rate and dehydration regimen on the histological appearance of human ovarian cortex following cryopreservation in 1, 2-propanediol.
Thin slices of human ovarian cortex were evaluated following cryopreservation in 1,2-propanediol (PROH)/sucrose under various conditions. Following rapid thawing, 1 microm sections were assessed by… Expand
Birth of a healthy infant after preimplantation confirmation of euploidy by comparative genomic hybridization.
- L. Wilton, R. Williamson, J. McBain, D. Edgar, L. Voullaire
- Medicine, Biology
- The New England journal of medicine
- 22 November 2001
Embryos that are transferred after in vitro fertilization frequently fail to implant in the uterus; in many cases, this failure is due to chromosomal abnormalities in the embryo. The current methods… Expand
Clinical outcomes following cryopreservation of blastocysts by vitrification or slow freezing: a population-based cohort study.
STUDY QUESTION What are the clinical efficacy and perinatal outcomes following transfer of vitrified blastocysts compared with transfer of fresh or of slow frozen blastocysts? SUMMARY ANSWER… Expand
A modified cryopreservation method increases the survival of human biopsied cleavage stage embryos.
BACKGROUND The relatively poor survival rate of human biopsied cleavage stage embryos following cryopreservation is a significant obstacle in the application of preimplantation genetic diagnosis… Expand
Development of antral follicles in human cryopreserved ovarian tissue following xenografting.
This study reports the first gross morphological and histological evidence of antral follicle development in human ovarian tissue following cryopreservation. Human ovarian tissue was cryopreserved… Expand
Oocyte maturation, follicle rupture and luteinization in human cryopreserved ovarian tissue following xenografting.
- D. Gook, D. Edgar, J. Borg, J. Archer, P. Lutjen, J. McBain
- Biology, Medicine
- Human reproduction
- 1 September 2003
BACKGROUND Previous studies have demonstrated development of antral follicles in cryopreserved human ovarian tissue after autografting and xenografting, thus indicating successful preservation of… Expand
Embryonic factors affecting outcome from single cryopreserved embryo transfer.
Multiple pregnancy minimization by single embryo transfer is becoming more prevalent, but is less common in the case of cryopreserved embryos. This study defines embryonic characteristics in single… Expand