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Piplartine, an amide alkaloid from Piper tuberculatum, presents anxiolytic and antidepressant effects in mice.
In the present work, we studied the effects of piplartine (PIP), an amide alkaloid isolated from the roots of Piper tuberculatum (Piperaceae), in the elevated plus maze, open field, rota rod,Expand
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Unequivocal assignments of flavonoids from Tephrosia sp. (Fabaceae)
1H and 13C NMR chemical shifts of praecansone B, pongaflavone and dehydrorotenone isolated from Tephrosia egregia Sandw and obovatin from T. toxicaria Pers. were unambiguously assigned by 1D and 2DExpand
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Essential Oil of Siparuna guianensis Aublet from the Amazon Region of Brazil
Abstract The essential oils obtained by steam distillation of the leaves, stem bark, stem wood, root bark, root wood and fruits of Siparuna guianensis were analyzed using a combination of GC/MS,Expand
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Cytotoxic withaphysalins from the leaves of Acnistus arborescens.
Three withaphysalins, rel-(17S,20R,22R)-5 beta,6 beta:18,20-diepoxy-4 beta-hydroxy-1,18-dioxowitha-2,24-dienolide(withaphysalin M) (1), rel-(17S,20R,22R)-5 beta,6 beta:18,20-diepoxy-4Expand
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Distribution of Iridoid Glucosides in Plants from the Genus Lippia (Verbenaceae): An investigation of Lippia alba (Mill.) N.E. Brown
The distribution of iridoid glucosides in plants from the genus Lippia (Verbenaceae) is described. In the present work, three known iridoids (theviridoside, mussaenoside and gardoside) were isolatedExpand
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Pro-erectile effects of an alkaloidal rich fraction from Aspidosperma ulei root bark in mice.
In recent years, there has been a renewed interest in the search for novel natural substances active against erectile dysfunction. Plants that belong to the genus Aspidosperma (Apocyanaceae) areExpand
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Glicoalcaloides antifúngicos, flavonoides e outros constituintes químicos de Solanum asperum
Two glycoalkaloids: solamargine and solasonine; three flavonoids: tiliroside, 7-O-α-L-ramnopyranosyl-kaempferol and 3-O-[s-D-glucopyranosyl-(1→6)-α-L-ramnopyranosyl]-7-Expand
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Natriuretic effect of bufalin in isolated rat kidneys involves activation of the Na+-K+-ATPase-Src kinase pathway.
Bufadienolides are structurally related to the clinically relevant cardenolides (e.g., digoxin) and are now considered as endogenous steroid hormones. Binding of ouabain to Na(+)-K(+)-ATPase has beenExpand
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Relaxant effect and possible mechanism of 17-nor-subincanadine E in rabbit corpora cavernosa.
Compounds with dual action on cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) may be a treatment option for erectile dysfunction, as they not only promote penileExpand
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