D. E. Atkinson

Publications131
h-index40
Citations9,729
Highly Influential Citations292
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The energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers.
An electrostatic spray apparatus and method for spraying electrically conductive coating materials on a continuous basis from an electrically grounded bulk coating supply. Included is a spray gun… Expand
Cellular Energy Metabolism and its Regulation
A solution to get the problem off, have you found it? Really? What kind of solution do you resolve the problem? From what sources? Well, there are so many questions that we utter every day. No matter… Expand
Adenylate Energy Charge in Escherichia coli During Growth and Starvation
TLDR
Tabulation of adenylate concentrations previously reported for various organisms and tissues supports the prediction, based on enzyme kinetic observations in vitro, that the energy charge is stabilized near 0.85 in intact metabolizing cells of a wide variety of types. Expand
Adenosine triphosphate conservation in metabolic regulation. Rat liver citrate cleavage enzyme.
TLDR
The "energy charge" of the adenylate system, defined as (ATP + ½ ADP)/(AMP + ADP + ATP), is proposed as a fundamental metabolic control parameter. Expand
Adenine nucleotide concentrations and turnover rates. Their correlation with biological activity in bacteria and yeast.
Publisher Summary The chapter reviews the correlations, both stoicheiometric and regulatory, that have been reported between the concentrations of the different adenine nucleotides and the occurrence… Expand
Stabilization of adenylate energy charge by the adenylate deaminase reaction.
TLDR
The activity of the enzyme decreases sharply as the size of the adenine nucleotide pool decreases in and below the physiological range, and this effect may be a self-limiting response to prevent excessive depletion of the pool. Expand
Adenosine Triphosphate Conservation in Metabolic Regulation
The citrate cleavage enzyme (EC 4.1.3.8) of rat liver is inhibited by adenosine diphosphate, which appears to compete with adenosine triphosphate. This effect may ensure that fatty acids are produced… Expand
Regulation of enzyme function.
TLDR
The author reveals the secrets of the successful and successful 3-C to 4-C conversions, as well as some of the challenges faced in accomplishing these conversions, in a single cycle. Expand
Biological feedback control at the molecular level.
Adenylate energy charge in Saccharomyces cerevisiae during starvation
TLDR
These results suggest that functional mitochondria or enzymes of balance of adenine nucleotides during starvation may be responsible for the engery charge responses of yeast to starvation and refeeding. Expand
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