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TWIST1 and BMI1 in Cancer Metastasis and Chemoresistance
Purpose Increasing evidences revealed that cancer cells with the characteristics of epithelial-mesenchymal transition (EMT) or cancer stem cells (CSC) have high ability of progression, invasion,… Expand
The role of C/EBP-α expression in human liver and liver fibrosis and its relationship with autophagy.
- LiLi Tao, Y. Zhai, D. Ding, W. Yin, Xiu-ping Liu, G. Yu
- Biology, Medicine
- International journal of clinical and…
- 1 October 2015
AIM To investigate the expression of CCAAT enhancer binding protein-α (C/EBP-α) in normal human liver and liver fibrosis and its probable association with autophagy. METHODS Double label… Expand
miR-320a is an independent prognostic biomarker for invasive breast cancer
Breast cancer is one of the most common malignancies worldwide and is the second leading cause of cancer-related mortality among females. miRNAs are a class of small noncoding RNAs that are… Expand
C/EBP-α ameliorates CCl4-induced liver fibrosis in mice through promoting apoptosis of hepatic stellate cells with little apoptotic effect on hepatocytes in vitro and in vivo
CCAAT enhancer binding protein-α (C/EBP-α) is a transcript factor that regulates adipocyte differentiation and induces apoptosis in hepatic stellate cells (HSCs) in vivo and in vitro. However, the… Expand
MicroRNA-320a inhibits breast cancer metastasis by targeting metadherin
Dysregulated microRNAs play important pathological roles in carcinogenesis that are yet to be fully elucidated. This study was performed to investigate the biological functions of microRNA-320a… Expand
Neurokinin-1 activation affects EGFR related signal transduction in triple negative breast cancer.
Breast cancers bear overexpression of neurokinin-1 (NK-1). The aim of this study was to investigate the relationship between NK-1 and EGFR in triple negative breast cancers (TNBCs).… Expand
Rab14 Suppression Mediated by MiR-320a Inhibits Cell Proliferation, Migration and Invasion in Breast Cancer
We found that microRNA-320a (miR-320a) was an attractive prognostic biomarker in breast cancer (BC) previously, whereas its regulatory mechanism in BC was not well understood. Our aim was to identify… Expand
Trichostatin A inhibits the activation of Hepatic stellate cells by Increasing C/EBP-α Acetylation in vivo and in vitro
Reversal of activated hepatic stellate cells (HSCs) to a quiescent state and apoptosis of activated HSCs are key elements in the reversion of hepatic fibrosis. CCAAT/enhancer binding protein α… Expand
Selective enrichment of N-linked glycopeptides and glycans by using a dextran-modified hydrophilic material.
- Linlin Chen, D. Ding, Qianying Sheng, Long Yu, Xiu-ping Liu, X. Liang
- Chemistry, Medicine
- Journal of separation science
- 1 May 2018
Glycosylation analysis of proteins from biological sources utilizing mass spectrometry based approaches is challenging due to the relatively low abundance of glycopeptides, the structural diversity… Expand
TSA increases C/EBP‑α expression by increasing its lysine acetylation in hepatic stellate cells.
CCAAT enhancer binding protein‑α (C/EBP‑α) is a transcription factor expressed only in certain tissues, including the liver. It has been previously demonstrated that C/EBP‑α may induce apoptosis in… Expand