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The microanatomic location of metastatic melanoma in sentinel lymph nodes predicts nonsentinel lymph node involvement.
PURPOSE Sentinel node biopsy is now widely accepted as the most accurate prognostic indicator in melanoma, and is important in guiding management of patients with clinical stage I or II disease.Expand
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Five years of sentinel node biopsy for melanoma: the St George's Melanoma Unit experience.
Sentinel node biopsy has become an integral part of the management of malignant melanoma. Here, the authors describe the technique that is used at the St George's Hospital Melanoma Unit. ResultsExpand
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Sentinel node biopsy in patients with in-transit recurrence of malignant melanoma.
Sentinel node biopsy (SNB) is now widely used for accurate staging of patients with clinical stage I or II malignant melanoma. We describe the use of SNB in five patients with in-transit recurrenceExpand
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The neutrophil–lymphocyte ratio and locoregional melanoma: a multicentre cohort study
Objectives The neutrophil–lymphocyte ratio (NLR) is an inflammatory biomarker which is useful in cancer prognostication. We aimed to investigate the differences in baseline NLR between patients withExpand
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The Morbidity of the Button-over-Nail Technique for Zone 1 Flexor Tendon Repairs. Should we still be using this Technique?
The button-over-nail technique is commonly used to fix the core suture to the distal phalanx for flexor digitorum profundus repairs in zone 1. We report a retrospective study of 23 consecutiveExpand
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Baseline Neutrophil–Lymphocyte and Platelet–Lymphocyte Ratios as Biomarkers of Survival in Cutaneous Melanoma: A Multicenter Cohort Study
BackgroundIn the peripheral blood, the neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) change in response to malignancy. These biomarkers are associated with adverse outcomes inExpand
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Potentiating Oncolytic Virus-Induced Immune-Mediated Tumor Cell Killing Using Histone Deacetylase Inhibition
A clinical oncolytic herpes simplex virus (HSV) encoding granulocyte-macrophage colony-stimulating factor (GM-CSF), talimogene laherparepvec, causes regression of injected and non-injected melanomaExpand
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Eleven-year survival from an intra-dermal melanoma.
Stage IV metastatic malignant melanoma of unknown primary (TxNxM1a) is known to have a poor prognosis. However, some patients suffering from cutaneous disease originally thought to representExpand
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Cutaneous Malignant Melanoma: Pathology and Management
Abstract Cutaneous malignant melanoma is a malignant skin tumour derived from melanocytes. In the UK, the incidence of new cases of malignant melanoma is around 8 per 100,000 per year for men and 11Expand
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