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Preliminary report: isolation of Ebola virus from monkeys imported to USA
This incident, the first in which a filovirus has been isolated from non-human primates without deliberate infection, raises the possibility that cynomolgus monkeys could be a reservoir of Ebola virus infection. Expand
Tumor incidence in a chemical carcinogenesis study of nonhuman primates.
Diethylnitrosamine (DENA) was the most potent and predictable hepatocarcinogen in cynomolgus, rhesus, and African green monkeys, and procarbazine was the only unequivocal carcinogen, with a 33% tumor incidence, causing acute nonlymphocytic leukemia in most of the cases. Expand
Enzyme immunosorbent assay for Ebola virus antigens in tissues of infected primates
The EIA, initially developed to detect antigens of prototype African strains of Ebola virus, reliably detected related strains of infection among imported, quarantined Macaca fascicularis monkeys in the United States. Expand
Combined simian hemorrhagic fever and Ebola virus infection in cynomolgus monkeys.
Simian hemorrhagic fever (SHF) virus and a new strain of Ebola virus were isolated concurrently in recently imported cynomolgus monkeys being maintained in a quarantine facility, suggesting a less virulent strain of virus. Expand
Effects of long-term oral administration of DDT on nonhuman primates
Clear evidence of hepatic and CNS toxicity following long-term DDT administration to cynomolgus and rhesus monkeys is shown, however, the two cases involving malignant tumors of different types are inconclusive with respect to a carcinogenic effect of DDT in nonhuman primates. Expand
Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rhesus monkeys (Macaca mulatta) following a single oral dose.
The oral LD50 of 2,3,7,8-tetrachlorodibenzo-p-dioxin in female rhesus monkeys was higher than the LD50 in rats following a single Oral Dose of dioxin. Expand
Transmission of type B viral hepatitis to chimpanzees.
This work presents a meta-analysis of 125 cases of Clostridium difficile infection over a 12-month period in eight patients at the University of North Carolina School of Medicine and shows clear patterns of infection that can be traced to E.coli A and B, respectively. Expand
Protection of monkeys against airborne tuberculosis by aerosol vaccination with bacillus Calmette-Guerin.
Bacillus Calmette-Guerin administered intravenously or by aerosol to rhesus monkeys induced a much greater degree of protection against aerosol challenge with virulent Mycobacterium tuberculosis thanExpand
Induction of osteogenic sarcomas and tumors of the hepatobiliary system in nonhuman primates with aflatoxin B1.
The results indicate that AFB1 is a potent hepatotoxin and carcinogen in nonhuman primates and further support the hypothesis that humans exposed to this substance may be at risk of developing cancer. Expand
Experimental infection of chimpanzees with the Norwalk agent of epidemic viral gastroenteritis
The availability of the chimpanzee as an experimental animal host susceptible to infection with the Norwalk agent should facilitate the study of epidemic viral gastroenteritis. Expand