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Dystrophin is required for the formation of stable muscle attachments in the zebrafish embryo
A class of recessive lethal zebrafish mutations has been identified in which normal skeletal muscle differentiation is followed by a tissue-specific degeneration that is reminiscent of the humanExpand
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Cadherin-mediated differential cell adhesion controls slow muscle cell migration in the developing zebrafish myotome.
Slow-twitch muscle fibers of the zebrafish myotome undergo a unique set of morphogenetic cell movements. During embryogenesis, slow-twitch muscle derives from the adaxial cells, a layer of paraxialExpand
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Competence to Stand Trial: A Neuropsychological Inquiry
How might the deconstruction of the legal theory of competence be related to modern neuropsychological models of cognition? To address this question, we examined retrospectively the relationshipExpand
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The relationship between perlecan and dystroglycan and its implication in the formation of the neuromuscular junction.
Perlecan is a major heparan-sulfate proteoglycan (HSPG) within the basement membrane surrounding skeletal muscle fibers. The C-terminus of its core protein contains three globular domain modulesExpand
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The role of heparin-binding growth-associated molecule (HB-GAM) in the postsynaptic induction in cultured muscle cells
The heparan sulfate proteoglycan (HSPGs) is a components of the extracellular matrix of skeletal muscle that is concentrated at the neuromuscular junction (NMJ). Recent studies have suggested thatExpand
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Myosin heavy chain expression in zebrafish and slow muscle composition
In the zebrafish embryo, two distinct classes of muscle fibers have been described in the forming myotome that arise from topographically separable precursor populations. Based entirely onExpand
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Concentration of pp125 focal adhesion kinase (FAK) at the myotendinous junction.
Focal adhesion kinase is a recently characterized tyrosine kinase that is concentrated at focal contacts in cultured cells. It is thought to play an important role in the regulation of theExpand
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Developmentally Restricted Actin-Regulatory Molecules Control Morphogenetic Cell Movements in the Zebrafish Gastrula
Although our understanding of the regulation of cellular actin and its control during the development of invertebrates is increasing, the question as to how such actin dynamics are regulatedExpand
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The Role of an Agrin–Growth Factor Interaction in ACh Receptor Clustering
The clustering of acetylcholine receptors (AChRs) at the neuromuscular junction is mediated in part by the heparan-sulfate proteoglycan agrin. However, our previous studies have also suggested theExpand
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Control of morphogenetic cell movements in the early zebrafish myotome.
As the vertebrate myotome is generated, myogenic precursor cells undergo extensive and coordinated movements as they differentiate into properly positioned embryonic muscle fibers. In the zebrafish,Expand
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