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Urinary-cell mRNA profile and acute cellular rejection in kidney allografts.
BACKGROUND The standard test for the diagnosis of acute rejection in kidney transplants is the renal biopsy. Noninvasive tests would be preferable. METHODS We prospectively collected 4300 urineExpand
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Messenger RNA for FOXP3 in the urine of renal-allograft recipients.
BACKGROUND The outcome of renal transplantation after an episode of acute rejection is difficult to predict, even with an allograft biopsy. METHODS We studied urine specimens from 36 subjects withExpand
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MicroRNA expression profiles predictive of human renal allograft status
Immune rejection of organ transplants is a life-threatening complication and is exemplified by alterations in the expression of protein-encoding genes. Because microRNAs (miRNAs) regulate theExpand
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Solid Organ Transplantation From Hepatitis B Virus–Positive Donors: Consensus Guidelines for Recipient Management
Use of organs from donors testing positive for hepatitis B virus (HBV) may safely expand the donor pool. The American Society of Transplantation convened a multidisciplinary expert panel thatExpand
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Noninvasive diagnosis of BK virus nephritis by measurement of messenger RNA for BK virus VP1 in urine1
Background. Polyoma virus type BK (BKV) nephritis has emerged as an important cause of renal allograft dysfunction and graft failure. Its diagnosis is contingent on the invasive procedure ofExpand
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Noninvasive detection of renal allograft inflammation by measurements of mRNA for IP-10 and CXCR3 in urine.
BACKGROUND We explored the hypothesis that measurements of mRNA encoding interferon-inducible protein-10 (IP-10) or the chemokine receptor CXCR3 in urinary cells offer a noninvasive means ofExpand
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Independent Risk Factors for Urinary Tract Infection and for Subsequent Bacteremia or Acute Cellular Rejection: A Single-Center Report of 1166 Kidney Allograft Recipients
Background Urinary tract infection (UTI) is a frequent, serious complication in kidney allograft recipients. Methods We reviewed the records of 1166 kidney allograft recipients who received theirExpand
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Gut microbiota dysbiosis and diarrhea in kidney transplant recipients
Posttransplant diarrhea is associated with kidney allograft failure and death, but its etiology remains unknown in the majority of cases. Because altered gut microbial ecology is a potential basisExpand
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Epidemiology of BK Virus in Renal Allograft Recipients: Independent Risk Factors for BK Virus Replication
Background. Identification of risk factors for BK virus (BKV) replication may improve transplant outcome. We investigated the impact of immunosuppressive drugs on the prevalence of BKV replication inExpand
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Report from the American Society of Transplantation on frailty in solid organ transplantation.
A consensus conference on frailty in kidney, liver, heart, and lung transplantation sponsored by the American Society of Transplantation (AST) and endorsed by the American Society of NephrologyExpand
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