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Invasive Infections Caused by Trichosporon Species and Geotrichum capitatum in Patients with Hematological Malignancies: a Retrospective Multicenter Study from Italy and Review of the Literature
TLDR
The optimal therapy for trichosporonosis has yet to be identified; however, in vitro experiences are providing encouraging evidence of the potential role of the new triazoles, in particular, voriconazole.
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Levofloxacin to prevent bacterial infection in patients with cancer and neutropenia.
TLDR
Prophylactic treatment with levofloxacin is an effective and well-tolerated way of preventing febrile episodes and other relevant infection-related outcomes in patients with cancer and profound and protracted neutropenia.
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Mucormycosis in hematologic patients.
TLDR
Mucormycosis is a rare filamentous fungal infection that occurs most frequently in neutropenic patients with acute leukemia, and although a reduction of mortality has been observed recently, the mortality rate still remains high.
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Drug sensitivity and clinical impact of members of the genus Kocuria.
TLDR
The published data on cultural, genotypic and clinical aspects of the genus Kocuria are reviewed, aiming to shed some light on these emerging nosocomial pathogens.
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Factors associated with adherence to and biofilm formation on polystyrene by Stenotrophomonas maltophilia: the role of cell surface hydrophobicity and motility.
TLDR
Hydrophobicity is a significant determinant of adhesion and biofilm formation on polystyrene surfaces in S. maltophilia and a highly significant negative correlation was observed between swimming motility and level of hydophobicity.
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Phenotypic and genotypic characterization of Stenotrophomonas maltophilia isolates from patients with cystic fibrosis: Genome diversity, biofilm formation, and virulence
TLDR
The phenotypic differences observed between CF and non-CF isolates may imply different selective conditions and persistence mechanisms in a hostile and heterogeneous environment such as CF lung.
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A multicenter, double-blind, placebo-controlled trial comparing piperacillin-tazobactam with and without amikacin as empiric therapy for febrile neutropenia.
TLDR
Responses were similar with both regimens, as were incidences of bacteremia and clinically documented and possible infections, and the initial empiric combination therapy was not associated with improved outcomes when compared with initial monotherapy.
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Infections caused by filamentous fungi in patients with hematologic malignancies. A report of 391 cases by GIMEMA Infection Program.
TLDR
A retrospective study shows that FFI still remains a life-threatening complication in neutropenic patients and that the use of glucocorticoids and recovery from neutropenia are the most important prognostic factors.
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Osteomyelitis and intervertebral discitis caused by Blastoschizomyces capitatus in a patient with acute leukemia
We describe the first known case of vertebral osteomyelitis and discitis caused by Blastoschizomyces capitatus in a leukemic patient and the results of therapy. We also reconfirm the microbiological…
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In Vitro Susceptibility Testing of Geotrichum capitatum: Comparison of the E-Test, Disk Diffusion, and Sensititre Colorimetric Methods with the NCCLS M27-A2 Broth Microdilution Reference Method
TLDR
Am amphotericin B and voriconazole appeared to be the more active drugs in vitro against 23 isolates of Geotrichum capitatum.
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