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The tumor suppressor adenomatous polyposis coli gene is associated with susceptibility to schizophrenia
The results indicate that adenomatous polyposis coli (APC), a tumor suppressor gene, may be a candidate gene conferring susceptibility to schizophrenia and also may be associated with reduced vulnerability to cancer in schizophrenia.
Analysis on speech signal features of manic patients.
The role of BDNF, NTRK2 gene and their interaction in development of treatment-resistant depression: data from multicenter, prospective, longitudinal clinic practice.
Serum trace element differences between Schizophrenia patients and controls in the Han Chinese population
Single element analysis indicated that the concentrations of cesium, zinc, and selenium were significantly reduced in patients with Schizophrenia in both the training and test groups, and information theory analysis suggested that Zinc could play roles independently in Sch schizophrenia.
The Interaction of BDNF and NTRK2 Gene Increases the Susceptibility of Paranoid Schizophrenia
The findings implied that single polymorphism of rs6265 rs1387923, rs2769605, and rs1565445 in BDNF and NTRK2 were not associated with the development of paranoid schizophrenia in a Han population, however, the interaction of BD NF and N TRK2 genes polymorphisms may be involved in the susceptibility to paranoid schizophrenia.
Measurement of Blood Thiamine Metabolites for Alzheimer's Disease Diagnosis
Brain-derived neurotrophic factor levels and bipolar disorder in patients in their first depressive episode: 3-year prospective longitudinal study.
- Zezhi Li, Chen Zhang, Y. Fang
- Psychology, BiologyThe British journal of psychiatry : the journal…
- 1 July 2014
The findings suggest that BDNF levels may serve as a potential differential diagnostic biomarker for bipolar disorder in a patient's first depressive episode.
Detecting Manic State of Bipolar Disorder Based on Support Vector Machine and Gaussian Mixture Model Using Spontaneous Speech
SVM provided an appropriate tool for detecting manic state for single patients, whereas GMM worked better for multiple patients’ manic state detection.
The involvement of N-methyl-D-aspartate receptor (NMDAR) subunit NR1 in the pathophysiology of schizophrenia.
This review discusses how disrupted function of NR1 subunits in NMDAR leads to the progression and development of symptoms of schizophrenia-like behaviors in a variety of genetically modified mouse models and suggests that the subunit-selective modulators ofNR1 sub units in NMDA receptors may be promising tools for the therapy of schizophrenia.