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3-Iodothyronamine is an endogenous and rapid-acting derivative of thyroid hormone
The discovery of 3-iodothyronamine (T1AM), a naturally occurring derivative of TH that in vitro is a potent agonist of the G protein–coupled trace amine receptor TAR1, suggests the existence of a new signaling pathway, stimulation of which leads to rapid physiological and behavioral consequences that are opposite those associated with excess TH. Expand
Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin
The zebrafish embryo is transparent and can tolerate absence of blood flow because its oxygen is delivered by diffusion rather than by the cardiovascular system. It is therefore possible to attribute… Expand
Cardiovascular development in embryos of the American alligator Alligator mississippiensis: effects of chronic and acute hypoxia
The main responses elicited by chronic hypoxic incubation, namely, cardiac enlargement, blunted hypoxic response and systemic vasodilation, may provide chronically hypoxic embryos with a new physiological repertoire for responding to hypoxia. Expand
Hypoxia elicits an increase in pulmonary vasculature resistance in anaesthetised turtles (Trachemys scripta).
- D. Crossley, J. Altimiras, T. Wang
- Biology, Medicine
- The Journal of experimental biology
- 15 December 1998
It is demonstrated that turtles exhibit hypoxic pulmonary vasoconstriction, although the threshold is low compared with that of mammals. Expand
Cardiovascular regulation during hypoxia in embryos of the domestic chicken Gallus gallus.
- D. Crossley, W. Burggren, J. Altimiras
- Biology, Medicine
- American journal of physiology. Regulatory…
In embryonic chickens, the only cardiovascular response to hypoxia that involves the CNS was the cholinergic regulation of arterial pressure after day 15 of incubation, therefore, although embryonic chickens and fetal sheep respond to Hypoxia with a similar redistribution of cardiac output, the underlying mechanisms differ between these species. Expand
Ontogeny of cholinergic and adrenergic cardiovascular regulation in the domestic chicken (Gallus gallus).
The data indicate that embryonic chickens rely primarily on adrenergic control of cardiovascular function, with no contribution from the parasympathetic nervous system. Expand
Ontogeny of baroreflex control in the American alligator Alligator mississippiensis
The findings indicate that embryonic development is a period of preparation for cardiovascular regulatory mechanisms that will be necessary in adult life and that the baroreflex control mechanism is required for cardiovascular control during ontogeny. Expand
The phylogeny and ontogeny of autonomic control of the heart and cardiorespiratory interactions in vertebrates
- E. Taylor, C. Leite, M. R. Sartori, Tobias Wang, A. Abe, D. Crossley
- Biology, Medicine
- Journal of Experimental Biology
- 1 March 2014
The heart in vertebrate embryos possesses both muscarinic cholinergic and β-adrenergic receptors very early in development, suggesting that it may be coordinated with the onset of central respiratory rhythmicity and subsequent breathing. Expand
Role of nitric oxide in the systemic and pulmonary circulation of anesthetized turtles (Trachemys scripta).
Effects of nitric oxide on vascular function in anesthetized Trachemys scripta are consistent with in vivo and in vitro studies on the systemic vasculature of different reptilian species, suggesting that NO has an important role in maintaining systemic vascular tone. Expand
Physiological variability in neonatal armadillo quadruplets: within- and between-litter differences.
A 'sibling effect' was attributed to the genetic components determining physiological characters in the nine-banded armadillo, confirming a 's sibling effect' that was always significantly less than between-litter variability. Expand