Author pages are created from data sourced from our academic publisher partnerships and public sources.
- Publications
- Influence
Isolation of a novel 38 residue-hypothalamic polypeptide which stimulates adenylate cyclase in pituitary cells.
- A. Miyata, A. Arimura, +5 authors D. Coy
- Chemistry, Medicine
- Biochemical and biophysical research…
- 16 October 1989
A novel neuropeptide which stimulates adenylate cyclase in rat anterior pituitary cell cultures was isolated from ovine hypothalamic tissues. Its amino acid sequence was revealed as:… Expand
Tissue distribution of PACAP as determined by RIA: highly abundant in the rat brain and testes.
- A. Arimura, A. Somogyvári-Vigh, A. Miyata, K. Mizuno, D. Coy, C. Kitada
- Biology, Medicine
- Endocrinology
- 1 November 1991
A heterologous RIA method for pituitary adenylate cyclase activating polypeptide with 38 residues (PACAP38) and a homologous RIA method for a shorter form of PACAP with 27 residues (PACAP27) were… Expand
Somatostatin receptor subtype specificity in human fetal pituitary cultures. Differential role of SSTR2 and SSTR5 for growth hormone, thyroid-stimulating hormone, and prolactin regulation.
- I. Shimon, J. Taylor, +6 authors S. Melmed
- Chemistry, Medicine
- The Journal of clinical investigation
- 15 February 1997
Somatostatin (SRIF), a hypothalamic inhibitor of pituitary growth hormone (GH) and thyroid-stimulating hormone (TSH) secretion, binds to five distinct receptor (SSTR) subtypes. We therefore tested… Expand
Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides.
- K. Raynor, W. Murphy, +5 authors T. Reisine
- Biology, Medicine
- Molecular pharmacology
- 1 June 1993
The recent molecular cloning of the genes encoding three somatostatin (SRIF) receptor subtypes has allowed for the individual expression of these receptors in mammalian cells and characterization of… Expand
Super-active analogs of growth hormone-releasing factor (1-29)-amide.
- V. Lance, W. Murphy, J. Sueiras-diaz, D. Coy
- Chemistry, Medicine
- Biochemical and biophysical research…
- 29 February 1984
Human pancreatic growth hormone releasing factor (1-29)-amide [hpGRF (1-29)-NH2] and the following analogs: [D-Tyr-1]-hpGRF(1-29)-NH2, [D-Ala-2]-hpGRF(1-29)-NH2, [D-Asp-3]-hpGRF(1-29)-NH2, and… Expand
Presence of highly selective receptors for PACAP (pituitary adenylate cyclase activating peptide) in membranes from the rat pancreatic acinar cell line AR 4‐2J
- L. Buscail, P. Gourlet, +7 authors J. Christophe
- Chemistry, Medicine
- FEBS letters
- 12 March 1990
We characterized highly selective receptors for PACAP, the pituitary adenylate cyclase activating peptide, in the tumoral acinar cell line AR 4‐2J derived from the rat pancreas. PACAP, a novel… Expand
RESPONSES TO ANALOGUES OF GROWTH HORMONE‐RELEASING HORMONE IN NORMAL SUBJECTS, AND IN GROWTH‐HORMONE DEFICIENT CHILDREN AND YOUNG ADULTS
- A. Grossman, M. Savage, +5 authors G. M. Besser
- Medicine
- Clinical endocrinology
- 1 September 1984
Three analogues of growth hormone‐releasing hormone (GHRH) have been compared in normal subjects. GHRH(1‐29)NH2 is equipotent to GHRH(1‐40); increasing doses from 10‐200 per subject augments the… Expand
Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas
- J. D. Heer, C. Rasmussen, D. Coy, J. Holst
- Biology, Medicine
- Diabetologia
- 16 September 2008
Aims/hypothesisThe glucose-lowering effect of glucagon-like peptide-1 (GLP-1) is based not only upon its potent insulinotropic actions but also on its ability to restrain glucagon secretion.… Expand
Lanthionine-somatostatin analogs: synthesis, characterization, biological activity, and enzymatic stability studies.
- G. Osapay, L. Prokai, +9 authors M. Goodman
- Chemistry, Medicine
- Journal of medicinal chemistry
- 4 July 1997
A series of cyclic somatostatin analogs containing a lanthionine bridge have been subjected to studies of structure-activity relationships. A direct synthesis of the thioether bridged analog (1) of… Expand
Examination of somatostatin involvement in the inhibitory action of GIP, GLP‐1, amylin and adrenomedullin on gastric acid release using a new SRIF antagonist analogue
- W. Rossowski, B. Cheng, N. Jiang, D. Coy
- Biology, Medicine
- British journal of pharmacology
- 1 November 1998
1 The effect of a new type 2 selective somatostatin (SRIF) receptor antagonist (DC‐41‐33) on somatostatin‐induced inhibition of pentagastrin‐stimulated gastric acid secretion in conscious, chronic… Expand