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Pressure injection of calcium both excites and adapts Limulus ventral photoreceptors
TLDR
The depolarization caused by injection of calcium arose from the activation of an inward current with rectification characteristics and a reversal potential that were similar to those of the light- activated conductance, which suggests that the same channels were activated by light and by calcium. Expand
INTERPHOTORECEPTOR RETINOID‐BINDING PROTEIN AND α‐TOCOPHEROL PRESERVE THE ISOMERIC AND OXIDATION STATE OF RETINOL
TLDR
Interphotoreceptor retinoid‐binding protein at low concentrations is found to protect retinol from isomerization and oxidation, and the addition of α‐tocopherol to either liposomes or an ethanolic‐buffer solution also prevents decomposition. Expand
Photoreceptor excitation and adaptation by inositol 1,4,5-trisphosphate
TLDR
In Limulus, intracellular pressure injection of InsP3 both excites and adapts ventral photoreceptors in a manner similar to light, and this results in new insights into the identity of the biochemical pathway that underlies phototransduction. Expand
A Visual Pigment Expressed in Both Rod and Cone Photoreceptors
TLDR
Results from immunohistochemistry, spectrophotometry, and single-cell RT-PCR demonstrate that, in the tiger salamander, the green rods and blue-sensitive cones contain the same opsin, suggesting that neither the cell topology or the transducin is sufficient to differentiate the rod and the cone response. Expand
Excitation and adaptation of Limulus ventral photoreceptors by inositol 1,4,5 triphosphate result from a rise in intracellular calcium
TLDR
In the same cells, the response to brief light flashes is slowed and diminished in amplitude by the injection of calcium buffer, but the charge transferred during the response is not significantly diminished, which suggests that light has access to a pathway of excitation in the presence of EGTA that is not accessible to intracellularly injected IP3. Expand
Excitation of Limulus photoreceptors by vanadate and by a hydrolysis-resistant analog of guanosine triphosphate.
TLDR
Discrete voltage fluctuations that occur spontaneously or in response to dim lights can be recorded from the ventral photoreceptors of Limulus, and these fluctuations are similar to those induced by light. Expand
Quantitative pressure injection of picoliter volumes into Limulus ventral photoreceptors.
TLDR
A calibration curve is obtained for quantitative estimates of injected volumes by injecting radioactively labeled sulfate into Limulus photoreceptor cells and finds that the estimates are accurate within a range covering one order of magnitude. Expand
Discrete-Wave Production in the Dark
�Molybdate, tungstate, fluoride, vanadate, and GTP-y-S [guanosine-5'-0-(3-thiotriphosphate)] were injected into Limulus ventral photoreceptors by ionophoresis from microelectrodes. All of these drugsExpand
Free calcium pulses following fertilization in the ascidian egg.
TLDR
It is inferred that the bulk (if not all) of the calcium required for both the fertilization pulse and the meiotic oscillations is released from internal sources. Expand
Molecular cloning of a rhodopsin gene from salamander rods.
TLDR
The cloned rhodopsin is a newly isolated member of the G protein-coupled receptor superfamily that is expressed in rods but not in cones and has been cloned and sequenced from the larval tiger salamander. Expand
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