The contraction or decrease in area of fatty acid monolayers maintained at a constant surface pressure of 16 dynes/cm was studied as a function of fatty acid chain length, unsaturation, temperature,… (More)
Both cyclosporine and bacterial lipopolysaccharide enhance prostanoid synthesis and regulate the immune response. This study was designed to establish whether these agents affect prostanoid synthesis… (More)
Lipid peroxidation was measured by the thio-barbituric assay for malondialdehyde (MDA). A small amount of MDA was formed when medial cells from guinea pig aorta were grown in tissue culture. The… (More)
Proceedings of the National Academy of Sciences…
2006
Quinones permeate our biotic environment, contributing to both homeostasis and cytotoxicity. All quinones generate reactive oxygen species through redox cycling, while partially substituted quinones… (More)
Cigarette smoking produces oxidant-mediated changes in the lung important to the pathogenesis of emphysema. Since vitamin E can neutralize reactive oxygen species and prevent peroxidation of… (More)
Ratios of the lipid monolayer area to the erythrocyte surface area are 2:1 at low surface pressures and approach 1: 1 at collapse pressures. Un saturated phospholipids in cholesterol-phospholipid… (More)
Primary cultures of smooth muscle cells were established from the medial layer of guinea pig aorta. Confluent cells at passage level 4–6 were challenged with arachidonic acid and treated with a… (More)
dl-alpha-Tocopherol spread on an acidic subphase as a gaseous monolayer was oxidized slowly to a derivative that was identified by thin-layer chromatography as alpha-tocopherylquinone. The derivative… (More)