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Great ape genetic diversity and population history
TLDR
This comprehensive catalogue of great ape genome diversity provides a framework for understanding evolution and a resource for more effective management of wild and captive great ape populations. Expand
The Simons Genome Diversity Project: 300 genomes from 142 diverse populations
TLDR
It is demonstrated that indigenous Australians, New Guineans and Andamanese do not derive substantial ancestry from an early dispersal of modern humans; instead, their modern human ancestry is consistent with coming from the same source as that of other non-Africans. Expand
Ancient human genomes suggest three ancestral populations for present-day Europeans
TLDR
It is shown that the great majority of present-day Europeans derive from at least three highly differentiated populations: West European Hunter-Gatherers (WHG), who contributed ancestry to all Europeans but not to Near Easterners; Ancient North Eurasians (ANE); and Early European Farmers (EEF), who were mainly of Near Eastern origin but also harbored WHG-related ancestry. Expand
Trading genes along the silk road: mtDNA sequences and the origin of central Asian populations.
TLDR
It seems unlikely that altitude has exerted a major selective pressure on mitochondrial genes in central Asian populations, because lowland and highland Kirghiz mtDNA sequences are very similar, and the analysis of molecular variance has revealed that the fraction of mitochondrial genetic variance due to altitude is not significantly different from zero. Expand
High-resolution analysis of human Y-chromosome variation shows a sharp discontinuity and limited gene flow between northwestern Africa and the Iberian Peninsula.
TLDR
The most striking results are that contemporary NW African and Iberian populations were found to have originated from distinctly different patrilineages and that the Strait of Gibraltar seems to have acted as a strong (although not complete) barrier to gene flow. Expand
Genomic insights into the origin of farming in the ancient Near East
We report genome-wide ancient DNA from 44 ancient Near Easterners ranging in time between ~12,000 and 1,400 bc, from Natufian hunter–gatherers to Bronze Age farmers. We show that the earliestExpand
The dawn of human matrilineal diversity.
TLDR
The tree phylogeny and coalescence calculations suggest that Khoisan matrilineal ancestry diverged from the rest of the human mtDNA pool 90,000-150,000 years before present and that at least five additional, currently extant maternal lineages existed during this period in parallel. Expand
Correlation between Genetic and Geographic Structure in Europe
TLDR
Although Affymetrix GeneChip 500K genotype data from 2,514 individuals belonging to 23 different subpopulations was investigated, the existing differences were characterized by a strong continent-wide correlation between geographic and genetic distance, which provided evidence for a spatial continuity of genetic diversity in Europe. Expand
Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture.
TLDR
The identification of two new mutations among Saudis and functional analyses in vitro support the convergent evolution of the LP in diverse populations, most probably reflecting different histories of adaptation to milk culture. Expand
Admixture, migrations, and dispersals in Central Asia: evidence from maternal DNA lineages
TLDR
The present results suggest that the mtDNA found out of Africa might be the result of a maturation phase, presumably in the Middle East or eastern Africa, that led to haplogroups M and N, and subsequently expanded into Eurasia, yielding a geographically structured group of external branches of these two haplog groups in western and eastern Eurasia. Expand
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