• Publications
  • Influence
Dual effects of macrophage inflammatory protein-1alpha on osteolysis and tumor burden in the murine 5TGM1 model of myeloma bone disease.
Recent data have implicated macrophage inflammatory protein-1alpha (MIP-1alpha) in multiple myeloma (MM)-associated osteolysis. However, it is unclear whether the chemokine's effects are direct, toExpand
  • 196
  • 7
  • PDF
The Mouse Bone Morphogenetic Protein-4 Gene
Bone morphogenetic protein-4 (BMP-4) is one of a member of related polypeptides that are important in bone formation and other developmental processes. We isolated the BMP-4 gene from a mouse genomicExpand
  • 94
  • 4
Signal transduction and biological functions of bone morphogenetic proteins.
Bone morphogenetic proteins (BMPs) are multi-functional growth factors and belong to the transforming growth factor beta (TGFbeta) superfamily. The roles of BMPs in embryonic development and cellularExpand
  • 113
  • 4
  • PDF
Systematic identification of the lysine succinylation in the protozoan parasite Toxoplasma gondii.
  • X. Li, X. Hu, +7 authors F. Tan
  • Biology, Medicine
  • Journal of proteome research
  • 17 November 2014
Lysine succinylation is a new posttranslational modification identified in histone proteins of Toxoplasma gondii, an obligate intracellular parasite of the phylum Apicomplexa. However, very little isExpand
  • 65
  • 2
Deer antler tissue contains two types of bone morphogenetic protein 4 mRNA transcripts.
Previously we isolated a bone morphogenetic protein 4 (BMP-4) cDNA from human prostate cancer cells and found that the 5' noncoding exon 1 of this BMP-4 cDNA was different from that of human boneExpand
  • 39
  • 2
Bone morphogenetic protein 2 transcripts in rapidly developing deer antler tissue contain an extended 5' non-coding region arising from a distal promoter.
To understand the regulation of the BMP-2 gene expression, we recently isolated the BMP-2 gene from a mouse genomic library and characterized the exon-intron structure and promoter. RNase protectionExpand
  • 41
  • 1
Cloning and sequence of bone morphogenetic protein 4 cDNA from fetal rat calvarial cell.
A cDNA clone encoding bone morphogenetic protein 4 (BMP 4) has been isolated from a primary fetal rat calvarial cell cDNA library. Sequencing of this clone has revealed a single open reading frameExpand
  • 29
  • 1
Identification of DNA methylation-driven genes in esophageal squamous cell carcinoma: a study based on The Cancer Genome Atlas
BackgroundAberrant DNA methylations are significantly associated with esophageal squamous cell carcinoma (ESCC). In this study, we aimed to investigate the DNA methylation-driven genes in ESCC byExpand
  • 20
  • 1
  • PDF
Pathogenesis of and major animal models used for nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) and its pathologically more severe form, nonalcoholic steatohepatitis (NASH), have become prevalent worldwide and carry an increased risk of developingExpand
  • 8
  • 1
Determination of the contents of EPA and DHA and lipid constituents in main fresh water fishes in China.
In this study the molecular formula and structure of lipid constituents of silver carp and bighead carp in middle reaches of Yangtze River were determined by gas chromatography-mass spectrometry. TheExpand
  • 1
  • 1