• Publications
  • Influence
Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force.
Endothelial function is thought to be an important factor in the pathogenesis of atherosclerosis, hypertension and heart failure. In the 1990s, high-frequency ultrasonographic imaging of the brachialExpand
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Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis
Endothelial dysfunction is an early event in experimental studies of atherogenesis, preceding formation of plaques. We have devised a non-invasive method for testing endothelial function, to find outExpand
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Updated clinical classification of pulmonary hypertension.
In 1998, a clinical classification of pulmonary hypertension (PH) was established, categorizing PH into groups which share similar pathological and hemodynamic characteristics and therapeuticExpand
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Haemodynamic definitions and updated clinical classification of pulmonary hypertension
Since the 1st World Symposium on Pulmonary Hypertension (WSPH) in 1973, pulmonary hypertension (PH) has been arbitrarily defined as mean pulmonary arterial pressure (mPAP) ≥25 mmHg at rest, measuredExpand
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The Assessment of Endothelial Function: From Research Into Clinical Practice
The discovery of nitric oxide (NO) as a crucial endothelium-derived molecule for vascular relaxation and the recognition of the endothelium as more than a passive interface between blood and theExpand
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Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women.
OBJECTIVES This study assessed whether aging is associated with progressive endothelial dysfunction, whether the pattern of any age-related decline in vascular health is different in men and womenExpand
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Endothelial dysfunction: does it matter? Is it reversible?
  • D. Celermajer
  • Medicine
  • Journal of the American College of Cardiology
  • 1 August 1997
Until recently, the endothelium was regarded as a relatively inert cell layer. However, over the past 20 years, research has revealed an extraordinary array of endothelial functions, includingExpand
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Sports-Related Sudden Death in the General Population
Background— Although such data are available for young competitive athletes, the prevalence, characteristics, and outcome of sports-related sudden death have not been assessed previously in theExpand
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Prevalence of rheumatic heart disease detected by echocardiographic screening.
BACKGROUND Epidemiologic studies of the prevalence of rheumatic heart disease have used clinical screening with echocardiographic confirmation of suspected cases. We hypothesized thatExpand
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Cigarette Smoking Is Associated With Dose‐Related and Potentially Reversible Impairment of Endothelium‐Dependent Dilation in Healthy Young Adults
BackgroundCigarette smoking is the most important modifiable risk factor for atherosclerosis. Endothelial dysfunction is an early event in atherogenesis, and we hypothesized that smoking might beExpand
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