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- Publications
- Influence
Conjugated system of homo-aza-steroidal esters in cancer chemotherapy.
- P. Catsoulacos, D. Catsoulacos
- Chemistry, Medicine
- Anticancer research
- 1 November 1994
The homo-aza-steroidal esters of conjugated carboxylic derivatives of nitrogen mustards are reviewed. Particularly we discuss the antitumor activity of cinnamic acid and benzoic acid mustard isomers,… Expand
Antitumor activity of homo-aza-steroidal esters of p-N, N-bis(2-chloroethyl)aminophenoxyacetic acid.
- P. Catsoulacos, D. Catsoulacos
- Chemistry, Medicine
- Anticancer research
- 1 July 1993
The homo-aza-steroidal esters of carboxylic derivatives of N, N-bis (2-chloroethyl) aniline are reviewed. In particular, we discuss the antitumor activity of the esters of homo-aza steroids in which… Expand
Hybrid anticancer compounds. Steroidal lactam esters of carboxylic derivatives of N,N-bis (2-chloroethyl) aniline (review).
- P. Catsoulacos, D. Catsoulacos
- Chemistry, Medicine
- Anticancer research
- 1 September 1991
For the rational design of more specific alkylating agents, we suggested new biological platforms able to deliver the alkylating moieties to specific target site and on the other hand we hoped to… Expand
Comparative study of sister chromatid exchange induction and antitumor effects by homo-aza-steroidal esters of [p-[bis(2-chloroethyl)amino]phenyl]butyric acid.
- C. Camoutsis, D. Catsoulacos, +5 authors S. Nikolaropoulos
- Biology, Medicine
- Cancer detection and prevention
- 2001
The present work was undertaken in order to test the hypothesis that the Sister Chromatid Exchange (SCE) assay in vitro can be used for the prediction of in vivo tumor response to newly synthesized… Expand
Reductive lithiation of alkyl phenyl sulfides in diethyl ether. A ready access to α,α-dialkylbenzyllithiums
- C. Screttas, Georgios A. Heropoulos, Maria Micha-Screttas, B. Steele, D. Catsoulacos
- Chemistry
- 21 July 2003
Diethyl ether is a convenient solvent for the conversion of benzylic phenyl sulfides to the corresponding organolithiums by an uncatalyzed reductive metalation, while catalysis by naphthalene is… Expand
An iminophosphine dendrimeric ligand and its evaluation in the Heck reaction
- D. Catsoulacos, B. Steele, Georgios A. Heropoulos, Maria Micha-Screttas, C. Screttas
- Chemistry
- 9 June 2003
Abstract DAB- dendr -(NH 2 ) 32 has been modified to produce two novel dendrimeric P , N -ligands, DAB- dendr -[1,2-(NCHC 6 H 4 PPh 2 )] 32 and DAB- dendr -[1,2-(NHCH 2 C 6 H 4 PPh 2 )] 32 . These… Expand
On the formation of homo‐aza‐steroids and derivatives by beckmann rearrangement. Antitumor activity of stereoisomers homo‐aza‐steroidal esters
- P. Catsoulacos, D. Catsoulacos
- Chemistry
- 1993
The Beckmann rearrangement of steroidal oximes is reported. Different methods of esterification of homo-aza-steroids with carboxylic derivatives of N,N-bis(2-chloroethyl)aniline are reported.
… Expand
A comparative study of the cytogenetic and antineoplastic effects induced by steroidal amidoesters of p-N, N-bis (2-chloroethyl) aminophenylbutyric acid (chlorambucil)
- A. Papageorgiou, P. Catsoulacos, +5 authors A. Kotsis
- Medicine
- 1996
L'effet de quatre stereoisomers d'amidoesters steroidaux avec de l'acide p-N, N-bis (2-chloroethyl) aminophenylbutyric (chlorambucil) sur les echanges de chromatides soeur (SCE) et sur les cinetiques… Expand
- 2
On the synthesis of pyrido[3,2,1-kl]phenothiazine, quino[8,1-bc][1,4]benzothiazepine and their derivatives
- P. Catsoulacos, D. Catsoulacos
- Chemistry
- 1 July 1992
This review article comprises tetracyclic rigid analogues of phenothiazine and dibenzothiazepine derivatives. In order to discover new useful drugs, the side chain of the heterocyclic nucleus is… Expand