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  • Dmitry Goldgaber, Michael I. Lerman, O. Wesley McBride, Umberto Saffiotti, D. Carleton Gajdusek
  • Biology, Medicine
  • Science
  • 1987 (First Publication: 20 February 1987)
  • Four clones were isolated from an adult human brain complementary DNA library with an oligonucleotide probe corresponding to the first 20 amino acids of the beta peptide of brain amyloid fromContinue Reading
  • Colin L. Masters, Jonathan O. Harris, D. Carleton Gajdusek, Clarence J. Gibbs, C. Bernoulli, David M. Asher
  • Medicine
  • Annals of neurology
  • 1979 (First Publication: 1 February 1979)
  • The worldwide epidemiology of Creutzfeldt-Jakob disease (CJD) is presented from an analysis of 1,435 patients. In the United States, the average annual mortality rate is at least 0.26 deaths perContinue Reading
  • Lev Goldfarb, Pamela Brown, +7 authors D. Carleton Gajdusek
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1991 (First Publication: 1 December 1991)
  • The PRNP gene, encoding the amyloid precursor protein that is centrally involved in Creutzfeldt-Jakob disease (CJD), has an unstable region of five variant tandem octapeptide coding repeats betweenContinue Reading
  • Richard Yanagihara, Herbert L. Amyx, D. Carleton Gajdusek
  • Biology, Medicine
  • Journal of virology
  • 1985 (First Publication: 1 July 1985)
  • Subclinical chronic infections characterized by transient viremia, prolonged virus shedding in oropharyngeal secretions and feces, and virus persistence in tissues (particularly lung) developed inContinue Reading
  • Dmitry Goldgaber, Hobart W. Harris, +5 authors D. Carleton Gajdusek
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 1989 (First Publication: 1 October 1989)
  • We have analyzed the modulation of amyloid beta-protein precursor (APP) gene expression in human umbilical vein endothelial cells (HUVEC). The level of the APP mRNA transcripts increased as HUVECContinue Reading
  • Piero Parchi, Shu Guang Chen, +9 authors Pierluigi Gambetti
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1998 (First Publication: 7 July 1998)
  • The clinicopathological phenotype of the Gerstmann-Sträussler-Scheinker disease (GSS) variant linked to the codon 102 mutation in the prion protein (PrP) gene (GSS P102L) shows a high heterogeneity.Continue Reading