ADENOSINE REGULATES VIA TWO DIFFERENT TYPES OF RECEPTORS, THE ACCUMULATION OF CYCLIC AMP IN CULTURED BRAIN CELLS
- D. Calker, Margarete Müller, B. Hamprecht
- Biology, ChemistryJournal of Neurochemistry
- 1 November 1979
Abstract— In cell cultures of glial character derived from perinatal mouse brain adenosine elicits two effects. (a) At submicromolar concentrations It inhibits the increase in the intracellular level…
P2X7‐dependent, but differentially regulated release of IL‐6, CCL2, and TNF‐α in cultured mouse microglia
- Chu‐Hsin Shieh, Annette Heinrich, T. Serchov, D. Calker, K. Biber
- BiologyGlia
- 1 April 2014
Analysis of the effects of ATP and BzATP on the production of six inflammatory mediators in cultured mouse primary microglia indicates that the P2X7‐dependent release of cytokines in micro glia is differentially regulated.
Increased Signaling via Adenosine A1 Receptors, Sleep Deprivation, Imipramine, and Ketamine Inhibit Depressive-like Behavior via Induction of Homer1a
- T. Serchov, H. Clement, D. Calker
- Psychology, BiologyNeuron
- 5 August 2015
Adenosine inhibits the accumulation of cyclic AMP in cultured brain cells
- D. Calker, Margarete Müller, B. Hamprecht
- BiologyNature
- 1 December 1978
It is reported here that the inhibition by adenosine of the increase in the intracellular level of cyclic AMP evoked by isoprenaline in cultured glioblasts is mediated by extracellular receptors.
The role of adenosine receptors in mood and anxiety disorders
- D. Calker, K. Biber, K. Domschke, T. Serchov
- Biology, PsychologyJournal of Neurochemistry
- 9 September 2019
The results discussed here indicate that the adenosinergic system is involved in both the etiology and the treatment of mood and anxiety disorders.
The Role of Glial Adenosine Receptors in Neural Resilience and the Neurobiology of Mood Disorders
Neuronal resilience is now considered as of pivotal importance in the neurobiology of mood disorders and their treatment, and Parameters closely related to adenosine receptor activation such as cerebral metabolic rate and delta power in the sleep EEG provide indirect evidence that adenosinergic signaling may be associated with the therapeutic response to these measures.
Sleep and the cholinergic rapid eye movement sleep induction test in patients with primary alcohol dependence
- H. Gann, B. Feige, F. Hohagen, D. Calker, Dagmar Geiss, R. Dieter
- Medicine, PsychologyBiological Psychiatry
- 1 September 2001
Inhibition of the High Affinity Myo-Inositol Transport System: A Common Mechanism of Action of Antibipolar Drugs?
- B. Lubrich, D. Calker
- BiologyNeuropsychopharmacology
- 1 October 1999
Carbamazepine-Induced Upregulation of Adenosine A1-Receptors in Astrocyte Cultures Affects Coupling to the Phosphoinositol Signaling Pathway
- K. Biber, B. Fiebich, P. Gebicke-Härter, D. Calker
- BiologyNeuropsychopharmacology
- 1 March 1999
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