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Temporal progression of angiogenesis and basal lamina deposition after contusive spinal cord injury in the adult rat
TLDR
This study demonstrates an angiogenic response, defined as SMI71/RECA‐1–immunopositive endothelial cells that colocalize with a robust deposition of basal lamina and basalLamina streamers, 7 days after injury within epicenter VGM, and proposes that therapies targetingAngiogenic processes be directed at the interval between 3 and 7 daysafter SCI.
Comparing Deficits Following Excitotoxic and Contusion Injuries in the Thoracic and Lumbar Spinal Cord of the Adult Rat
TLDR
It is demonstrated that gray matter loss can result in significant functional deficits, including paraplegia, in the absence of a disruption of major descending pathways.
Functional Redundancy of Ventral Spinal Locomotor Pathways
TLDR
A diffuse arrangement of axons within the ventral white matter that may comprise a system of multiple descending pathways subserving spontaneous over-ground locomotion in the intact animal is supported.
Incidence rates and populations at risk for spinal cord injury: A regional study
TLDR
A higher proportion of older adults with SCI was observed for this region compared to other studies, and greater effort is warranted in emphasizing the potential risks of combining driving with alcohol consumption and non-use of seatbelts.
Functional consequences of lumbar spinal cord contusion injuries in the adult rat.
TLDR
The data suggest that moderately-severe contusion injuries centered on the rostral segments of the lumbar enlargement induce more severe locomotor deficits than would be predicted by the histological outcome (spared white matter), suggesting that gray matter loss may play a role in functional deficits following some lUMBar contusions.
Adult rat forelimb dysfunction after dorsal cervical spinal cord injury
TLDR
The present study revealed that both anatomically and electrophysiologically complete myelotomies of the C4 spinal cord dorsal columns significantly increased the adult rat's averaged times to first attend to adhesive stickers placed on the palms of their forepaws at 1 week.
Both Dorsal and Ventral Spinal Cord Pathways Contribute to Overground Locomotion in the Adult Rat
TLDR
The data indicate that significant contributions to locomotion from myelinated pathways within the rat DLF can be revealed when combined with simultaneous compromise of the VLF.
The Role of Directly Applied Hypothermia in Spinal Cord Injury
TLDR
The results demonstrate that there is a statistically significant improvement in neurologic function in rats subjected to hypothermia (19 C) after insertion of a spacer that induced an ischemic spinal cord injury, indicating that directly applied Hypothermia may be beneficial in preventing injury secondary to ischeMIC cellular damage.
Hindlimb Immobilization in a Wheelchair Alters Functional Recovery Following Contusive Spinal Cord Injury in the Adult Rat
TLDR
It is hypothesized that incompletely injured rats maximally retrain themselves while moving about in their cages over the first few weeks postinjury, and hindlimb immobilization and passive stretch may hinder or conceal the normal course of functional recovery of spinal cord injured rats.
The Effect of Cigarette Smoking and Smoking Cessation on Spinal Fusion
TLDR
Results validate the hypothetical assumption that postoperative smoking cessation helps to reverse the impact of cigarette smoking on outcome after spinal fusion.
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