• Publications
  • Influence
Genome reduction in Leptospira borgpetersenii reflects limited transmission potential
TLDR
It is concluded that L. borgpetersenii is evolving toward dependence on a strict host-to-host transmission cycle, similar to L. interrogans, a species with minimal genetic decay and that survives extended passage in aquatic environments encountering a mammalian host. Expand
Genome Sequence of the Saprophyte Leptospira biflexa Provides Insights into the Evolution of Leptospira and the Pathogenesis of Leptospirosis
TLDR
It is suggested that once incorporated into the L. biflexa genome, laterally transferred DNA undergoes minimal rearrangement due to physical restrictions imposed by high gene density and limited presence of transposable elements, in contrast to the genomes of pathogenic Leptospira species undergo frequent rearrangements. Expand
Group II nucleopolyhedrovirus subgroups revealed by phylogenetic analysis of polyhedrin and DNA polymerase gene sequences.
TLDR
Correlations of virus and host evolution within Group II taxa are discussed and methods and data developed will allow rapid sequencing of NPV DNA polymerase genes are developed. Expand
Global Analysis of Outer Membrane Proteins from Leptospira interrogans Serovar Lai
TLDR
Global analysis of the cellular location and expression of leptospiral proteins will be useful in the annotation of genomic sequence data and in providing insight into the biology of Leptospira. Expand
Effects of Temperature on Gene Expression Patterns in Leptospira interrogans Serovar Lai as Assessed by Whole-Genome Microarrays
TLDR
Temperature is an important factor regulating expression of proteins that facilitate invasion and establishment of disease in Leptospira spp. Expand
Comparative Analysis of the First Complete Enterococcus faecium Genome
TLDR
The complete 3.0-Mb genome sequence of the multilocus sequence type 17 vancomycin-resistant Enterococcus faecium strain Aus0004, isolated from the bloodstream of a patient in Melbourne, Australia, in 1998, is reported. Expand
Leptospira fainei sp. nov., isolated from pigs in Australia.
TLDR
Cultures of uteri and kidneys from two pigs herds in New South Wales and Victoria (Australia) yielded five strains identified as Leptospira on morphological and cultural grounds, satisfying the criterion of a new species, Leptonospira fainei (type strain BUT 6T). Expand
Prospective Whole-Genome Sequencing Enhances National Surveillance of Listeria monocytogenes
TLDR
It is demonstrated that WGS performed prospectively for national epidemiologic surveillance of Listeria monocytogenes has the capacity to be superior to current approaches using pulsed-field gel electrophoresis (PFGE), multilocus sequence typing (MLST),Multilocus variable-number tandem-repeat analysis (MLVA), binary typing, and serotyping. Expand
Functional Identification of Conjugation and Replication Regions of the Tetracycline Resistance Plasmid pCW3 from Clostridium perfringens
TLDR
Detailed molecular analysis of the tetracycline resistance plasmid pCW3 from C. perfringens has shown that it represents the prototype of a unique family of conjugative antibiotic resistance and virulence plasmids, and provides evidence that a nonreplicating Tn916-like element can evolve to become the conjugation locus of replicatingPlasmids that carry major virulence genes or antibiotic resistance determinants. Expand
Shiga toxin-producing Escherichia coli strains negative for locus of enterocyte effacement.
TLDR
Comparison of the genetic composition of the virulence plasmids of STEC pO113 and pO157 from LEE-negative andLEE-positive STEC strains showed several clonal groups, suggesting that pathogenic L EE-negative STEC has emerged several times throughout its evolution. Expand
...
1
2
3
4
5
...