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Cernunnos, a Novel Nonhomologous End-Joining Factor, Is Mutated in Human Immunodeficiency with Microcephaly
DNA double-strand breaks (DSBs) occur at random upon genotoxic stresses and represent obligatory intermediates during physiological DNA rearrangement events such as the V(D)J recombination in theExpand
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Latex provocation tests in patients with spina bifida: who is at risk of becoming symptomatic?
BACKGROUND Although there is accepted information on the prevalence rates of sensitization to latex in patients with spina bifida, little is known about the clinical relevance of this sensitization.Expand
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Cloning, expression, and characterization of recombinant Hev b 3, a Hevea brasiliensis protein associated with latex allergy in patients with spina bifida.
BACKGROUND Two natural rubber latex proteins, Hev b 1 and Hev b 3, have been described in spina bifida (SB)-associated latex allergy. OBJECTIVE The aim of this study was to clone and express Hev bExpand
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Hev b 7 is a Hevea brasiliensis protein associated with latex allergy in children with spina bifida.
BACKGROUND In addition to their disease-associated handicaps, patients with spina bifida (SB) are at high risk of developing latex allergy. Individuals with SB represent a special group ofExpand
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Oculocutaneous albinism accompanied by minor morphologic stigmata and reduced number and function of NK cells. A new variant of NK cell defect?
We describe the case of a 7-year-old girl with an apparently new genetic disorder characterized by oculocutaneous albinism, microcephaly, low-set helices, a prominent nose with a broad bridge, a longExpand
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Ventricular shunts and the prevalence of sensitization and clinically relevant allergy to latex in patients with spina bifida
Patients with spina bifida represent the highest‐risk group for developing hypersensitivity to latex. Recognized risk factors for these patients are repeated surgery and an atopic disposition. OurExpand
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Rapid Production of Recombinant Allergens in Nicotiana benthamiana and Their Impact on Diagnosis and Therapy
Background: Type I allergies are immunological disorders that afflict a quarter of the world’s population. Recombinant allergens have improved the diagnosis of allergic diseases and allow theExpand
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Latex allergy in spina bifida: at the turning point?
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Characterization of T Cell Responses to Hev b 3, an Allergen Associated with Latex Allergy in Spina Bifida Patients1
The prevalence of type I allergy to Hevea brasiliensis latex is particularly high among individuals with frequent exposure such as health care workers and patients with spina bifida (SB). Due to aExpand
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Effects of latex avoidance on latex sensitization, atopy and allergic diseases in patients with spina bifida
To cite this article: Blumchen K, Bayer P, Buck D, Michael T, Cremer R, Fricke C, Henne T, Peters H, Hofmann U, Keil T, Schlaud M, Wahn U, Niggemann B. Effects of latex avoidance on latexExpand
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