• Publications
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Role of Hydrogen Sulfide in the Development of Atherosclerotic Lesions in Apolipoprotein E Knockout Mice
  • Y. Wang, Xia Zhao, +7 authors J. Du
  • Medicine, Biology
  • Arteriosclerosis, thrombosis, and vascular…
  • 1 February 2009
Objective—We explored the effect of hydrogen sulfide (H2S) on atherosclerotic progression, particularly on intracellular adhesion molecule-1 (ICAM-1) in apolipoprotein-E knockout (apoE−/−) mice andExpand
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Exome sequencing reveals mutations in TRPV3 as a cause of Olmsted syndrome.
Olmsted syndrome (OS) is a rare congenital disorder characterized by palmoplantar and periorificial keratoderma, alopecia in most cases, and severe itching. The genetic basis for OS remainedExpand
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  • 14
Open Access
Mutations in the cyp51A gene and susceptibility to itraconazole in Aspergillus fumigatus serially isolated from a patient with lung aspergilloma.
OBJECTIVES To monitor changes in itraconazole susceptibility of isolates from a patient undergoing treatment for pulmonary Aspergillus infection and relate these changes to genotypic/phenotypicExpand
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Open Access
Castleman's tumours and production of autoantibody in paraneoplastic pemphigus
BACKGROUND Paraneoplastic pemphigus is an autoimmune mucocutaneous disease associated with Castleman's tumours, which when surgically removed often result in great improvement of mucocutaneousExpand
  • 104
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Family history of von Hippel–Lindau disease was uncommon in Chinese patients: suggesting the higher frequency of de novo mutations in VHL gene in these patients
Von Hippel–Lindau (VHL) disease is an autosomal dominant familial cancer syndrome caused by germline mutations in VHL tumor suppressor gene. It is characterized by hemangioblastoma in central nervousExpand
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[The regulatory effect of endogenous hydrogen sulfide on hypoxic pulmonary hypertension].
  • C. Zhang, J. Du, +4 authors C. Tang
  • Medicine, Biology
  • Beijing da xue xue bao. Yi xue ban = Journal of…
  • 1 October 2003
OBJECTIVE To study the changes of endogenous H2S and the effect of exogenously applied H2S on hypoxic pulmonary hypertension (HPH). METHODS Male Wistar rats were randomly divided into control groupExpand
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Common genetic variants of the human uromodulin gene regulate transcription and predict plasma uric acid levels.
Uromodulin (UMOD) genetic variants cause familial juvenile hyperuricemic nephropathy, characterized by hyperuricemia with decreased renal excretion of UMOD and uric acid, suggesting a role for UMODExpand
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The Polymorphisms in LNK Gene Correlated to the Clinical Type of Myeloproliferative Neoplasms
Objective LNK is an adapter protein negatively regulating the JAK/STAT cell signaling pathway. In this study, we observed the correlation between variation in LNK gene and the clinical type ofExpand
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Open Access
Epitopes in the linker subdomain region of envoplakin recognized by autoantibodies in paraneoplastic pemphigus patients.
Sera from paraneoplastic pemphigus (PNP) immunoprecipitate multiple antigens from human epidermal protein extract. In this study, we further characterized the autoantibodies in 12 PNP sera.Expand
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Screening of common mitochondrial mutations in Chinese patients with mitochondrial encephalomyopathies.
To investigate the spectrum of common mitochondrial mutations in Northern China during the years of 2000-2005, 552 patients of mitochondrial encephalomyopathies clinically diagnosed as MELAS, MERRFExpand
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