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New opportunities in crystal engineering--the role of atomic force microscopy in studies of molecular crystals.
Here, we highlight recent research involving atomic force microscopy investigations of molecular crystals, and focus particularly on the latest relevant advances in our knowledge of crystal-growthExpand
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Supramolecular control of reactivity in the solid state: from templates to ladderanes to metal-organic frameworks.
We describe how reactivity can be controlled in the solid state using molecules and self-assembled metal-organic complexes as templates. Being able to control reactivity in the solid state bearsExpand
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Disappearing Polymorphs Revisited
Nearly twenty years ago, Dunitz and Bernstein described a selection of intriguing cases of polymorphs that disappear. The inability to obtain a crystal form that has previously been prepared isExpand
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"Click" labeling strategy for M(CO)(3) (M = Re, (99m)Tc) prostate cancer targeted flutamide agents.
Two distinct "click" chemistry labeling approaches were investigated with dipyridylamine alkyne derivatives and M(CO)(3)(+) (M = Re, (99m)Tc). The triazole ring was found uncoordinated and wasExpand
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A "hidden" co-crystal of caffeine and adipic acid.
Co-crystal formation between caffeine and adipic acid has been explored over the years without success; utilizing the newly developed co-crystal screening method, we have finally discovered thisExpand
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Divergent prebiotic synthesis of pyrimidine and 8-oxo-purine ribonucleotides
Understanding prebiotic nucleotide synthesis is a long standing challenge thought to be essential to elucidating the origins of life on Earth. Recently, remarkable progress has been made, but to dateExpand
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The curious case of (caffeine)·(benzoic acid): how heteronuclear seeding allowed the formation of an elusive cocrystal
Cocrystals are modular multicomponent solids with exceptional utility in synthetic chemistry and materials science. A variety of methods exist for the preparation of cocrystals, yet, some promisingExpand
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Prebiotic selection and assembly of proteinogenic amino acids and natural nucleotides from complex mixtures
A central problem for the prebiotic synthesis of biological amino acids and nucleotides is to avoid the concomitant synthesis of undesired or irrelevant by-products. Additionally, multistep pathwaysExpand
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Sonocrystallization yields monoclinic paracetamol with significantly improved compaction behavior.
Ultrasound-assisted crystallization (sonocrystallization) was used to prepare a mixture of nano- and micrometer-sized crystals of the monoclinic form of paracetamol-a widely used analgesic known forExpand
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