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- Publications
- Influence
Guidelines for performing skin tests withdrugs in the investigation of cutaneous adverse drug reactions
- A. Barbaud, M. Gonçalo, D. Bruynzeel, A. Bircher
- Medicine
- Contact dermatitis
- 1 December 2001
Skin testing with a suspected drug has been reported to be helpful in determining the cause of cutaneous adverse drug reactions (CADR). Many isolated reports of positive drug skin tests are… Expand
Dendritic cells: biology of the skin
- M. J. Toebak, S. Gibbs, D. Bruynzeel, R. Scheper, T. Rustemeyer
- Medicine
- Contact dermatitis
- 1 January 2009
Allergic contact dermatitis results from a T‐cell‐mediated, delayed‐type hypersensitivity immune response induced by allergens. Skin dendritic cells (DCs) play a central role in the initiation of… Expand
Monitoring levels of preservative sensitivity in Europe
- J. Wilkinson, S. Shaw, +14 authors J. Wahlberg
- Medicine
- Contact dermatitis
- 1 April 2002
A 10‐year multicentre analysis of the frequency of sensitivity to common preservatives collected in 16 centres in 11 countries has shown stable but persisting high levels of sensitivity to… Expand
CXCL8 secretion by dendritic cells predicts contact allergens from irritants.
- M. J. Toebak, P. Pohlmann, +5 authors S. Gibbs
- Chemistry, Medicine
- Toxicology in vitro : an international journal…
- 1 February 2006
Monocyte-derived dendritic cell functions have been explored for identification of contact allergens in vitro. Current methods, including measurement of changes in cell surface marker expression… Expand
The CXCR3 activating chemokines IP-10, Mig, and IP-9 are expressed in allergic but not in irritant patch test reactions.
- J. Flier, D. Boorsma, +5 authors C. P. Tensen
- Medicine
- The Journal of investigative dermatology
- 1 October 1999
Differentiation between allergic and irritant contact dermatitis reactions is difficult, as both inflammatory diseases are clinically, histologically, and immunohistologically very similar. Previous… Expand
Photopatch testing: a consensus methodology for Europe
- D. Bruynzeel, J. Ferguson, +11 authors A. Tanew
- Medicine
- Journal of the European Academy of Dermatology…
- 1 November 2004
A group of interested European Contact Dermatologists/Photobiologists met to produce a consensus statement on methodology, test materials and interpretation of photopatch testing. While it is… Expand
Hand eczema severity and quality of life: a cross‐sectional, multicentre study of hand eczema patients
- T. Agner, K. Andersen, +9 authors T. Diepgen
- Medicine
- Contact dermatitis
- 1 July 2008
Background and Objectives: Hand eczema is a chronic disease with negative impact on quality of life (QoL). In this study, QoL in hand eczema patients is assessed and related to age, sex, severity,… Expand
CXCL12 is essential for migration of activated Langerhans cells from epidermis to dermis
- K. Ouwehand, S. Santegoets, D. Bruynzeel, R. Scheper, T. D. de Gruijl, S. Gibbs
- Biology, Medicine
- European journal of immunology
- 1 November 2008
The initial step in Langerhans cell (LC) migration from the epidermis to the lymph node involves migration of maturing LC into the dermis. Here, we investigated the migration of LC out of the… Expand
Monitoring the European standard series in 10 centres 1996–2000
- D. Bruynzeel, T. Diepgen, +9 authors J. Wilkinson
- Medicine
- Contact dermatitis
- 1 September 2005
A 5‐year retrospective study of the frequency of sensitization to the 25 allergens of the European standard series (ESS) was conducted in 10 centres in 8 European countries. Included were the results… Expand
Corticosteroid contact allergy: an EECDRG multicentre study
- A. Dooms-Goossens, K. E. Andersen, +11 authors J. Wilkinson
- Medicine
- Contact dermatitis
- 1 July 1996
This article describes the results of an EECDRG multicentre study on contact allergy to corticosteroids. A total of 7238 patients were investigated: 6238 in 13 centres in the course of 1993, and 1000… Expand