• Publications
  • Influence
Acrylamide: a review of its genotoxicity and an assessment of heritable genetic risk.
TLDR
Using data from the studies generating quantitative information concerning heritability of genetic effects, an assessment of the heritable genetic risk presented by acrylamide is presented and estimates for inhalation or dermal exposures suggest higher risks for induced genetic disease in offspring from fathers exposed in occupational settings. Expand
Overview: the history, technical function and safety of rebaudioside A, a naturally occurring steviol glycoside, for use in food and beverages.
TLDR
This paper summarizes the information used to conclude that high purity rebaudioside A (rebiana) produced to food-grade specifications and according to Good Manufacturing Practices is safe for human consumption under its intended conditions of use as a general purpose sweetener. Expand
A comparison of the genotoxic properties of tris(2,3-dibromopropyl)phosphate and tris(1,3-dichloro-2-propyl)phosphate in a battery of short-term bioassays.
: Neonatal hormone treatments with estradiol, progesterone, testosterone, cortisol, or especially diethylstilbestrol (DES) were found to alter the immune responsiveness of spleen cells from femaleExpand
A critical review of the genetic toxicity of steviol and steviol glycosides.
  • D. Brusick
  • Chemistry, Medicine
  • Food and chemical toxicology : an international…
  • 1 July 2008
TLDR
Application of a Weight-of-Evidence approach to assess the genetic toxicology database concludes that stevioside and steviol do not pose a risk of genetic damage following human consumption. Expand
Reproducibility of microbial mutagenicity assays: II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escherichia coli.
TLDR
The intra- and interlaboratory reproducibility of the Salmonella assay with regard to the overall judgment of mutagenic or nonmutagenic was good, but the results in the E coli strain exhibited a high degree of variability between laboratories. Expand
Principles of Genetic Toxicology
TLDR
Applications of Genetic Toxicology to Environmental and Human Monitoring.- Monitoring Techniques.- Occupational Monitoring.- Environmental Monitoring.- References. Expand
Genotoxicity of radiofrequency radiation
TLDR
Data from studies conducted in a frequency range from 800 to 3,000 MHz were reviewed and subjected to a weight‐of‐evidence evaluation, which focused on direct toxicological effects of RFR as well as on studies addressing basic biological responses to RFR at the cellular and molecular level. Expand
Critical assessment of the genetic toxicity of naphthalene.
  • D. Brusick
  • Medicine, Chemistry
  • Regulatory toxicology and pharmacology : RTP
  • 1 July 2008
TLDR
Based on the data reviewed in this report, it is not apparent that genetic lesions produced by naphthalene or any of its metabolites drive the tumorigenic activity. Expand
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