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The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo.
The organization of the anterior pattern in the Drosophila embryo is mediated by the maternal effect gene bicoid. bcd has been identified in an 8.7‐kb genomic fragment by germ line transformants thatExpand
The genome of the model beetle and pest Tribolium castaneum
Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agriculturalExpand
Molecular Characterization of the Key Switch F Provides a Basis for Understanding the Rapid Divergence of the Sex-Determining Pathway in the Housefly
The housefly, Musca domestica, is an excellent model system to study the diversification of the pathway that specifies the sexual fate. A number of different mechanisms have been described in theExpand
The Drosophila orb RNA-binding protein is required for the formation of the egg chamber and establishment of polarity.
The orb gene of Drosophila encodes sex-specific germ-line proteins that contain two RRM-type RNA-binding domains. Here we report the distribution of Orb protein in wild-type, tumorous, and orb mutantExpand
The transformer2 gene in Musca domestica is required for selecting and maintaining the female pathway of development
We present the isolation and functional analysis of a transformer2 homologue Mdtra2 in the housefly Musca domestica. Compromising the activity of this gene by injecting dsRNA into embryos causesExpand
Genome of the house fly, Musca domestica L., a global vector of diseases with adaptations to a septic environment
BackgroundAdult house flies, Musca domestica L., are mechanical vectors of more than 100 devastating diseases that have severe consequences for human and animal health. House fly larvae play a vitalExpand
Structure of the segmentation gene paired and the Drosophila PRD gene set as part of a gene network
The sequence of paired, a pair-rule gene required for segmentation in Drosophila, is presented. A search for genes with domains homologous to the paired gene was initiated and three homologues from aExpand
Developmental distribution of female-specific Sex-lethal proteins in Drosophila melanogaster.
The binary switch gene Sex-lethal (Sxl) must be on in females and off in males to allow the proper elaboration of the appropriate sexual developmental pathway in Drosophila melanogaster. PreviousExpand
The Ceratitis capitata homologue of the Drosophila sex-determining gene sex-lethal is structurally conserved, but not sex-specifically regulated.
In Drosophila, Sxl functions as a binary switch in sex determination. Under the control of the primary sex-determining signal, it produces functional protein only in XX animals to implement femaleExpand
Isolation of the paired gene of Drosophila and its spatial expression during early embryogenesis
We have cloned the paired gene of Drosophila melanogaster, a pair-rule gene required for the establishment of proper segmentation. The transcriptional pattern in young embryos shows developmentalExpand