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Modulation of endothelial cell proliferation, adhesion, and motility by recombinant heparin‐binding domain and synthetic peptides from the type I repeats of thrombospondin
The results suggest that both the Trp‐Ser‐Xaa‐Trp sequences in the type I repeats and the amino‐terminal domain play roles in the antiproliferative activity of thrombospondin.
Serum Cadmium Levels in Pancreatic Cancer Patients from the East Nile Delta Region of Egypt
The results from this pilot study suggest that pancreatic cancer in the East Nile Delta region is significantly associated with high levels of serum cadmium and farming.
Detection of Heavy Metals by Immunoassay: Optimization and Validation of a Rapid, Portable Assay for Ionic Cadmium
An immunoassay is described that measured Cd(II) in aqueous samples at concentrations from approximately 7 to 500 ppb. The assay utilized a monoclonal antibody that bound tightly to a
Apolipoprotein E: A potent inhibitor of endothelial and tumor cell proliferation
Recombinant human apolipoprotein E3, purified from E. coli, inhibited the proliferation of several cell types, including endothelial cells and tumor cells in a dose‐ and time‐dependent manner and suggest that apoE may be effective in modulating angiogenesis, tumor cell growth, and metastasis.
Matrix stimulates the proliferation of human corneal endothelial cells in culture.
The use of substratum elaborated by bovine corneal endothelial cells has proved useful in the preparation of human endothelial cell cultures from juvenile and adult donors.
Preparation of specific monoclonal antibodies (MAbs) against heavy metals: MAbs that recognize chelated cadmium ions.
Spike-recovery studies in tap and stream water showed that the most sensitive antibody can be used for cadmium detection in drinking water.
Antibody-based sensors for heavy metal ions.
The KinExA 3000 instrument and the Cd(II)-specific antibody were used to construct a prototype assay that could correctly assess the concentration of cadmium spiked into a groundwater sample.
One-step competitive immunoassay for cadmium ions: development and validation for environmental water samples.
The rapid, simple, and reliable competitive immunoassay was developed and validated for measurement of Cd(II) in environmental water samples and compared favorably with graphite furnace atomic absorption spectroscopy in its ability to accurately measure Cd (II) spiked into water samples from a Louisiana bayou.
Heparin- and sulfatide-binding peptides from the type I repeats of human thrombospondin promote melanoma cell adhesion.
The type I peptides of thrombospondin define a distinct class of heparin-binding peptides that promote melanoma cell adhesion when immobilized on plastic and inhibit heparIn-dependent binding of thROMbosponin or laminin to human melanoma cells.
Metal Binding Properties of a Monoclonal Antibody Directed toward Metal-Chelate Complexes*
A monoclonal antibody that recognizes cadmium-EDTA complexes has been produced by the injection of BALB/c mice with a metal-chelate complex covalently coupled to a carrier protein. The ability of