• Publications
  • Influence
Biological Insights From 108 Schizophrenia-Associated Genetic Loci
TLDR
Associations at DRD2 and several genes involved in glutamatergic neurotransmission highlight molecules of known and potential therapeutic relevance to schizophrenia, and are consistent with leading pathophysiological hypotheses. Expand
Common variants on chromosome 6p22.1 are associated with schizophrenia
TLDR
It is demonstrated that common schizophrenia susceptibility alleles can be detected and the characterization of these signals will suggest important directions for research on susceptibility mechanisms. Expand
Genome-wide association study identifies five new schizophrenia loci
TLDR
The role of common genetic variation in schizophrenia in a genome-wide association study of substantial size is examined, suggesting MIR137-mediated dysregulation as a previously unknown etiologic mechanism in schizophrenia. Expand
A family study of obsessive-compulsive disorder.
TLDR
The findings suggest that an anxiety disorder diathesis is transmitted in families with OCD, but that its expression within these families is variable and support the current practice of classifying OCD as anxiety disorder. Expand
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
TLDR
Empirical evidence of shared genetic etiology for psychiatric disorders can inform nosology and encourages the investigation of common pathophysiologies for related disorders. Expand
A review of compulsive buying disorder.
  • D. Black
  • Medicine
  • World psychiatry : official journal of the World…
  • 1 February 2007
TLDR
CBD is associated with significant psychiatric comorbidity, particularly mood and anxiety disorders, substance use disorders, eating disorders, and other disorders of impulse control. Expand
Characteristics of 36 subjects reporting compulsive sexual behavior.
TLDR
Compulsive sexual behavior may be a clinically useful concept, but it describes a heterogeneous group of individuals with substantial psychiatric comorbidity and diverse behavioral problems. Expand
Borderline personality disorder in male and female offenders newly committed to prison.
TLDR
Borderline personality disorder is relatively common among both male and female offenders in prison, and is associated with substantial psychologic stress and impaired quality of life. Expand
Systems Training for Emotional Predictability and Problem Solving (STEPPS) for outpatients with borderline personality disorder: a randomized controlled trial and 1-year follow-up.
TLDR
STEPPS, an adjunctive group treatment, can deliver clinically meaningful improvements in borderline personality disorder-related symptoms and behaviors, enhance global functioning, and relieve depression. Expand
Clinical features and psychiatric comorbidity of subjects with pathological gambling behavior.
TLDR
The results confirm that individuals with pathological gambling suffer substantial psychiatric comorbidity and support continued inclusion of pathological gambling in the diagnostic category of impulse control disorders. Expand
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