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Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting.
BACKGROUND We examined the efficacy of olanzapine for the prevention of nausea and vomiting in patients receiving highly emetogenic chemotherapy. METHODS In a randomized, double-blind, phase 3… Expand
Toxicology and pharmacological action of anabaena flos-aquae toxin.
Calves, rats, ducks, and goldfish given lethal oral doses of bacteria-free lyophilized cell suspensions of toxic Anabaena flos-aquae died as a result of respiratory arrest. Experiments with selected… Expand
Pharmacology of anatoxin-a, produced by the freshwater cyanophyte Anabaena flos-aquae NRC-44-1.
- W. Carmichael, D. Biggs, M. Peterson
- Biology, Medicine
- Toxicon : official journal of the International…
Abstract Anatoxin-a (ANTX-A) is the neuromuscular blocking agent produced by the freshwater cyanophyte Anabaena flos-aquae (Lyngb.) de Breb. strain NRC-44-1. Its pharmacological properties have been… Expand
Two laboratory case studies on the oral toxicity to calves of the freshwater cyanophyte (blue-green alga) Anabaena flos-aquae NRC-44-1.
Employer and employment agency attitudes towards employing individuals with mental health needs
- D. Biggs, N. Hovey, P. Tyson, S. Macdonald
- Psychology, Medicine
- Journal of mental health
- 1 December 2010
Background: The positive benefits of paid employment for individuals with mental health needs are well known yet many still remain unemployed (Perkins & Rinaldi, (). Unemployment rates among patients… Expand
EXPERIMENTS ON THE MECHANISM OF ACTION OF CHLOROCRESOL AND CAFFEINE.
- D. Biggs
- Chemistry, Medicine
- British journal of pharmacology and chemotherapy
- 1 April 1965
Phenols are known to cause contraction of skeletal muscle. Thus Torda & Wolff (1945a) reported that phenol (1 mg/ml.) caused a contraction of the frog rectus abdominis muscle, and Cori & Cori (1936)… Expand
Simultaneous GLC estimation of salicylic acid and aspirin in plasma.
- L. J. Walter, D. Biggs, R. T. Coutts
- Chemistry, Medicine
- Journal of pharmaceutical sciences
- 1 November 1974
Abstract: Plasma salicylates, salicylic acid and acetylsalicylic acid (aspirin), were estimated as their respective trimethylsilyl derivatives by GLC. The method involved the use of fluoride and… Expand
Capsaicin selectively reduces airway responses to histamine, substance P and vagal stimulation.
Airway responsiveness to histamine, substance P, methacholine and bilateral electrical vagal stimulation was assessed in capsaicin-treated and control guinea pigs. In animals treated with capsaicin… Expand
Low‐dose methotrexate kinetics in arthritis
- J. Edelman, D. Biggs, F. Jamali, A. Russell
- Clinical pharmacology and therapeutics
- 1 March 1984
Twelve patients with either rheumatoid or psoriatic arthritis were injected with a 10‐mg bolus dose of methotrexate (MTX) either intramuscularly (n = 6) or intravenously (n = 6) and the MTX… Expand
Does capsaicin cause reflex bronchospasm in guinea-pigs?
Capsaicin given intravenously (i.v.) into the vena cava or intra-arterially (i.a.) into the aortic arch of anesthetized guinea-pigs induced dose-dependent increases in pulmonary-flow resistance (R)… Expand