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Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting.
BACKGROUND We examined the efficacy of olanzapine for the prevention of nausea and vomiting in patients receiving highly emetogenic chemotherapy. METHODS In a randomized, double-blind, phase 3Expand
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Toxicology and pharmacological action of anabaena flos-aquae toxin.
Calves, rats, ducks, and goldfish given lethal oral doses of bacteria-free lyophilized cell suspensions of toxic Anabaena flos-aquae died as a result of respiratory arrest. Experiments with selectedExpand
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Pharmacology of anatoxin-a, produced by the freshwater cyanophyte Anabaena flos-aquae NRC-44-1.
Abstract Anatoxin-a (ANTX-A) is the neuromuscular blocking agent produced by the freshwater cyanophyte Anabaena flos-aquae (Lyngb.) de Breb. strain NRC-44-1. Its pharmacological properties have beenExpand
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Employer and employment agency attitudes towards employing individuals with mental health needs
Background: The positive benefits of paid employment for individuals with mental health needs are well known yet many still remain unemployed (Perkins & Rinaldi, (). Unemployment rates among patientsExpand
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  • D. Biggs
  • Chemistry, Medicine
  • British journal of pharmacology and chemotherapy
  • 1 April 1965
Phenols are known to cause contraction of skeletal muscle. Thus Torda & Wolff (1945a) reported that phenol (1 mg/ml.) caused a contraction of the frog rectus abdominis muscle, and Cori & Cori (1936)Expand
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Simultaneous GLC estimation of salicylic acid and aspirin in plasma.
Abstract: Plasma salicylates, salicylic acid and acetylsalicylic acid (aspirin), were estimated as their respective trimethylsilyl derivatives by GLC. The method involved the use of fluoride andExpand
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Capsaicin selectively reduces airway responses to histamine, substance P and vagal stimulation.
Airway responsiveness to histamine, substance P, methacholine and bilateral electrical vagal stimulation was assessed in capsaicin-treated and control guinea pigs. In animals treated with capsaicinExpand
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Low‐dose methotrexate kinetics in arthritis
Twelve patients with either rheumatoid or psoriatic arthritis were injected with a 10‐mg bolus dose of methotrexate (MTX) either intramuscularly (n = 6) or intravenously (n = 6) and the MTXExpand
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Does capsaicin cause reflex bronchospasm in guinea-pigs?
  • D. Biggs, V. Goel
  • Chemistry, Medicine
  • European journal of pharmacology
  • 10 September 1985
Capsaicin given intravenously (i.v.) into the vena cava or intra-arterially (i.a.) into the aortic arch of anesthetized guinea-pigs induced dose-dependent increases in pulmonary-flow resistance (R)Expand
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