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Redefine statistical significance
The default P-value threshold for statistical significance is proposed to be changed from 0.05 to 0.005 for claims of new discoveries in order to reduce uncertainty in the number of discoveries.
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
A joint (multi-phenotype) analysis of educational attainment and three related cognitive phenotypes generates polygenic scores that explain 11–13% of the variance ineducational attainment and 7–10% ofthe variance in cognitive performance, which substantially increases the utility ofpolygenic scores as tools in research.
Genome-wide association study identifies 74 loci associated with educational attainment
Because educational attainment is measured in large numbers of individuals, it will continue to be useful as a proxy phenotype in efforts to characterize the genetic influences of related phenotypes, including cognition and neuropsychiatric diseases.
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Three genetic loci are found to explain variation associated with educational achievement and provide promising candidate SNPs for follow-up work, and effect size estimates can anchor power analyses in social-science genetics.
WHO IS 'BEHAVIORAL'? COGNITIVE ABILITY AND ANOMALOUS PREFERENCES.
- D. Benjamin, Sebastian. Brown, Jesse M. Shapiro
- EconomicsJournal of the European Economic Association
- 1 December 2013
Evidence from a new laboratory study of Chilean high-school students with similar schooling backgrounds shows that small-stakes risk aversion and short-run discounting are less common among those with higher standardized test scores, providing suggestive evidence of a possible causal impact of cognitive resources on expressed preferences.
Multi-trait analysis of genome-wide association summary statistics using MTAG
Applying MTAG to summary statistics for depressive symptoms, neuroticism and subjective well-being increased discovery of associated loci as compared to single-trait analyses, yielding more informative bioinformatics analyses and increasing the variance explained by polygenic scores by approximately 25%, matching theoretical expectations.
Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses
Across the phenotypes, loci regulating expression in central nervous system and adrenal or pancreas tissues are strongly enriched for association and the two loci associated with depressive symptoms replicate in an independent depression sample.
What Do You Think Would Make You Happier? What Do You Think You Would Choose?
- D. Benjamin, Ori Heffetz, Miles S. Kimball, A. Rees-Jones
- PsychologyThe American economic review
- 27 July 2011
Key factors-such as predicted sense of purpose, control over one's life, family happiness, and social status-that help explain hypothetical choice controlling for predicted SWB are identified.
Who is 'Behavioral'? Cognitive Ability and Anomalous Preferences
In this paper, we ask whether variation in preference anomalies is related to variation in cognitive ability. Evidence from a new laboratory study of Chilean high school students shows that…
Errors in Probabilistic Reasoning and Judgment Biases
- D. Benjamin
- PsychologyHandbook of Behavioral Economics - Foundations…
- 1 October 2018
Errors in probabilistic reasoning have been the focus of much psychology research and are among the original topics of modern behavioral economics. This chapter reviews theory and evidence on this…