D. Bell

Publications12
h-index11
Citations11,545
Highly Influential Citations352
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Integrated Genomic Analyses of Ovarian Carcinoma
TLDR
It is reported that high-grade serous ovarian cancer is characterized by TP53 mutations in almost all tumours (96%); low prevalence but statistically recurrent somatic mutations in nine further genes including NF1, BRCA1,BRCA2, RB1 and CDK12; 113 significant focal DNA copy number aberrations; and promoter methylation events involving 168 genes.
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The Immune Landscape of Cancer
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Comprehensive Characterization of Cancer Driver Genes and Mutations
View on Elsevier
Oncogenic Signaling Pathways in The Cancer Genome Atlas
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Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients.
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Pathogenic Germline Variants in 10,389 Adult Cancers
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Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context
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Ovarian cancer is a heterogeneous disease.
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Early loss of heterozygosity on 17q in ovarian cancer. The Abe Ovarian Cancer Genetics Group.
TLDR
Comparison of all malignant tumours presenting with either localized or widespread FIGO stage I/II or widespread disease showed that, particularly on 17q, allele loss increases in the more advanced stages, and the findings suggest that an important tumour-suppressor gene may be located in the region 17q23-qter.
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The utility of tissue transglutaminase as a marker of apoptosis during treatment and progression of prostate cancer.
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