Author pages are created from data sourced from our academic publisher partnerships and public sources.
Share This Author
Integrated Genomic Analyses of Ovarian Carcinoma
It is reported that high-grade serous ovarian cancer is characterized by TP53 mutations in almost all tumours (96%); low prevalence but statistically recurrent somatic mutations in nine further genes including NF1, BRCA1,BRCA2, RB1 and CDK12; 113 significant focal DNA copy number aberrations; and promoter methylation events involving 168 genes.
The Immune Landscape of Cancer
Comprehensive Characterization of Cancer Driver Genes and Mutations
Oncogenic Signaling Pathways in The Cancer Genome Atlas
Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients.
Pathogenic Germline Variants in 10,389 Adult Cancers
Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context
Ovarian cancer is a heterogeneous disease.
Early loss of heterozygosity on 17q in ovarian cancer. The Abe Ovarian Cancer Genetics Group.
Comparison of all malignant tumours presenting with either localized or widespread FIGO stage I/II or widespread disease showed that, particularly on 17q, allele loss increases in the more advanced stages, and the findings suggest that an important tumour-suppressor gene may be located in the region 17q23-qter.