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Operant Reward Learning in Aplysia: Neuronal Correlates and Mechanisms
Operant conditioning is a form of associative learning through which an animal learns about the consequences of its behavior. Here, we report an appetitive operant conditioning procedure inAplysiaExpand
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Identification and characterization of catecholaminergic neuron B65, which initiates and modifies patterned activity in the buccal ganglia of Aplysia.
Catecholamines are believed to play an important role in regulating the properties and functional organization of the neural circuitry mediating consummatory feeding behaviors in Aplysia. In theExpand
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Contingent-Dependent Enhancement of Rhythmic Motor Patterns: AnIn Vitro Analog of Operant Conditioning
Operant conditioning is characterized by the contingent reinforcement of a designated behavior. Previously, feeding behavior inAplysia has been demonstrated to be modified by operant conditioning,Expand
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In Vitro Analog of Operant Conditioning inAplysia. I. Contingent Reinforcement Modifies the Functional Dynamics of an Identified Neuron
Previously, an analog of operant conditioning inAplysia was developed using the rhythmic motor activity in the isolated buccal ganglia. This analog expressed a key feature of operant conditioning,Expand
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Dopaminergic synapses mediate neuronal changes in an analogue of operant conditioning.
Feeding behavior in Aplysia can be modified by operant conditioning in which contingent reinforcement is conveyed by the esophageal nerve (E n.). A neuronal analogue of this conditioning in theExpand
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Serotonergic modulation of two potassium currents in the pleural sensory neurons of Aplysia.
1. The properties of membrane currents that were modulated by serotonin (5-HT) were investigated with two-electrode voltage-clamp techniques in sensory neuron somata isolated from the pleuralExpand
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Modulation of fictive feeding by dopamine and serotonin in aplysia.
The buccal ganglia of Aplysia contain a central pattern generator (CPG) that mediates rhythmic movements of the buccal apparatus during feeding. Activity in this CPG is believed to be regulated, inExpand
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Modeling Circadian Oscillations with Interlocking Positive and Negative Feedback Loops
Both positive and negative feedback loops of transcriptional regulation have been proposed to be important for the generation of circadian rhythms. To test the sufficiency of the proposed mechanisms,Expand
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In Vitro Analog of Operant Conditioning inAplysia. II. Modifications of the Functional Dynamics of an Identified Neuron Contribute to Motor Pattern Selection
Previously, an analog of operant conditioning was developed using the buccal ganglia of Aplysia, the probabilistic occurrences of a specific motor pattern (i.e., pattern I), a contingentExpand
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Differential effects of cAMP and serotonin on membrane current, action-potential duration, and excitability in somata of pleural sensory neurons of Aplysia.
1. In somata of sensory neurons in the pleural ganglia of Aplysia californica, serotonin (5-HT) modulates at least three K+ currents: the S K+ current (IK,S), a slow component of the Ca2(+)-activatedExpand
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