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MicroRNAs Genomics, Biogenesis, Mechanism, and Function
- D. Bartel
- 23 January 2004
Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets
MicroRNAs: Target Recognition and Regulatory Functions
- D. Bartel
- 23 January 2009
Predicting effective microRNA target sites in mammalian mRNAs
It is shown that recently reported non-canonical sites do not mediate repression despite binding the miRNA, which indicates that the vast majority of functional sites are canonical.
MicroRNA targeting specificity in mammals: determinants beyond seed pairing.
Most mammalian mRNAs are conserved targets of microRNAs.
This work overhauled its tool for finding preferential conservation of sequence motifs and applied it to the analysis of human 3'UTRs, increasing by nearly threefold the detected number of preferentially conserved miRNA target sites.
Prediction of Mammalian MicroRNA Targets
Computational identification of plant microRNAs and their targets, including a stress-induced miRNA.
Prediction of Plant MicroRNA Targets
MicroRNAS and their regulatory roles in plants.
The importance of miRNA-directed gene regulation during plant development is now particularly clear and typically at the cores of gene regulatory networks, targeting genes that are themselves regulators, such as those encoding transcription factors and F-box proteins.