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Urinary Creatinine Concentrations in the U.S. Population: Implications for Urinary Biologic Monitoring Measurements
TLDR
The normal range of urinary creatinine concentrations among various demographic groups are documented, the impact that variations in creatinin concentrations can have on classifying exposure status of individuals in epidemiologic studies are evaluated, and an approach using multiple regression to adjust for variations in Creatinine in multivariate analyses is recommended. Expand
Urinary levels of seven phthalate metabolites in the U.S. population from the National Health and Nutrition Examination Survey (NHANES) 1999-2000.
We measured the urinary monoester metabolites of seven commonly used phthalates in approximately 2,540 samples collected from participants of the National Health and Nutrition Examination SurveyExpand
Prenatal Exposure to Organophosphate Pesticides and IQ in 7-Year-Old Children
TLDR
Prenatal but not postnatal urinary DAP concentrations were associated with poorer intellectual development in 7-year-old children, higher but nonetheless within the range of levels measured in the general U.S. population. Expand
Urinary Concentrations of Metabolites of Pyrethroid Insecticides in the General U.S. Population: National Health and Nutrition Examination Survey 1999–2002
TLDR
The presence of its metabolites in the urine of U.S. residents indicates that children may have higher exposures to pyrethroid insecticides than adolescents and adults, and the presence of 3-phenoxybenzoic acid, a metabolite common to many pyrethoid insecticides, in more than 70% of the samples. Expand
Impact of prenatal chlorpyrifos exposure on neurodevelopment in the first 3 years of life among inner-city children.
TLDR
Children exposed to higher, compared with lower, chlorpyrifos levels were significantly more likely to experience Psychomotor Development Index and Mental Development Index delays, attention problems, attention-deficit/hyperactivity disorder problems, and pervasive developmental disorder problems at 3 years of age. Expand
Organophosphate Pesticide Exposure and Neurodevelopment in Young Mexican-American Children
TLDR
Pregnant and child OP urinary metabolite levels were negatively associated with MDI, but child measures were positively associated and both prenatal and postnatal DAPs were associated with risk of pervasive developmental disorder at 24 months of age. Expand
Variability and Predictors of Urinary Bisphenol A Concentrations during Pregnancy
TLDR
Urinary high-molecular-weight phthalate and serum tobacco smoke metabolite concentrations were positively associated with BPA concentrations, suggesting numerous sources of BPA exposure during pregnancy. Expand
Prenatal Exposure to Organophosphates, Paraoxonase 1, and Cognitive Development in Childhood
TLDR
It is suggested that prenatal exposure to organophosphates is negatively associated with cognitive development, particularly perceptual reasoning, with evidence of effects beginning at 12 months and continuing through early childhood. Expand
Effects of transplacental exposure to environmental pollutants on birth outcomes in a multiethnic population.
TLDR
Evidence that environmental pollutants at levels currently encountered in New York City adversely affect fetal development is provided. Expand
Association of in Utero Organophosphate Pesticide Exposure and Fetal Growth and Length of Gestation in an Agricultural Population
TLDR
These associations with gestational age may be biologically plausible given that organophosphate pesticides depress cholinesterase and acetylcholine stimulates contraction of the uterus, and despite these observed associations, the rate of preterm delivery in this population was lower than in a U.S. reference population. Expand
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