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Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF
- P. Wan, M. Garnett, R. Marais
- Biology, ChemistryCell
- 19 March 2004
Structure of the mitotic checkpoint complex
- W. Chao, K. Kulkarni, Ziguo Zhang, E. Kong, D. Barford
- BiologyNature
- 21 March 2012
TLDR
The Crystal Structure of Human Eukaryotic Release Factor eRF1—Mechanism of Stop Codon Recognition and Peptidyl-tRNA Hydrolysis
- Haiwei Song, P. Mugnier, D. Barford
- Biology, ChemistryCell
- 4 February 2000
Crystal structure of the protein serine/threonine phosphatase 2C at 2.0 A resolution.
- A. Das, N. Helps, P. Cohen, D. Barford
- Biology, ChemistryThe EMBO journal
- 1 December 1996
TLDR
The structure of the tetratricopeptide repeats of protein phosphatase 5: implications for TPR‐mediated protein–protein interactions
- A. Das, P. Cohen, D. Barford
- Biology, ChemistryThe EMBO journal
- 2 March 1998
TLDR
Wild-type and mutant B-RAF activate C-RAF through distinct mechanisms involving heterodimerization.
- M. Garnett, S. Rana, H. Paterson, D. Barford, R. Marais
- BiologyMolecular cell
- 22 December 2005
Crystal structure of an activated Akt/Protein Kinase B ternary complex with GSK3-peptide and AMP-PNP
- Jing Yang, P. Cron, V. Good, Vivienne Thompson, B. Hemmings, D. Barford
- Biology, ChemistryNature Structural Biology
- 1 December 2002
TLDR
Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation.
- Jing Yang, P. Cron, D. Barford
- Biology, ChemistryMolecular cell
- 1 June 2002
Molecular discrimination of structurally equivalent Lys 63‐linked and linear polyubiquitin chains
- D. Komander, Francisca E. Reyes-Turcu, J. Licchesi, P. Odenwaelder, K. Wilkinson, D. Barford
- BiologyEMBO reports
- 1 May 2009
TLDR
Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate
- A. Salmeen, J. Andersen, D. Barford
- Chemistry, BiologyNature
- 12 June 2003
TLDR
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