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Antiretroviral prophylaxis for HIV prevention in heterosexual men and women.
BACKGROUND Antiretroviral preexposure prophylaxis is a promising approach for preventing human immunodeficiency virus type 1 (HIV-1) infection in heterosexual populations. METHODS We conducted a… Expand
Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis.
CONTEXT Adherence to antiretroviral therapy is a powerful predictor of survival for individuals living with human immunodeficiency virus (HIV) and AIDS. Concerns about incomplete adherence among… Expand
Adherence to HAART: A Systematic Review of Developed and Developing Nation Patient-Reported Barriers and Facilitators
Background Adherence to highly active antiretroviral therapy (HAART) medication is the greatest patient-enabled predictor of treatment success and mortality for those who have access to drugs. We… Expand
Mobile phone technologies improve adherence to antiretroviral treatment in a resource-limited setting: a randomized controlled trial of text message reminders
Objective:There is limited evidence on whether growing mobile phone availability in sub-Saharan Africa can be used to promote high adherence to antiretroviral therapy (ART). This study tested the… Expand
Barriers to Antiretroviral Adherence for Patients Living with HIV Infection and AIDS in Botswana
- S. Weiser, William L. Wolfe, +8 authors R. Marlink
- Journal of acquired immune deficiency syndromes
- 1 November 2003
Background: Botswana has the highest rate of HIV infection in the world, estimated at 36% among the population aged 15‐49 years. To improve antiretroviral (ARV) treatment delivery, we conducted a… Expand
Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population
ObjectiveTo examine the relationship between adherence, viral suppression and antiretroviral resistance in HIV-infected homeless and marginally housed people on protease inhibitor (PI) therapy.… Expand
Routine HIV Testing in Botswana: A Population-Based Study on Attitudes, Practices, and Human Rights Concerns
Background The Botswana government recently implemented a policy of routine or “opt-out” HIV testing in response to the high prevalence of HIV infection, estimated at 37% of adults. Methods and… Expand
Adherence is not a barrier to successful antiretroviral therapy in South Africa
Objective: to determine adherence of an indigent African HIV‐infected cohort initiating antiretroviral therapy (ART); to identify predictors of incomplete adherence (< 95%) and virologic failure (>… Expand
Non-adherence to highly active antiretroviral therapy predicts progression to AIDS.
The introduction of highly active antiretroviral therapy (HAART) has produced a dramatic reduction in mortality among HIV-infected individuals [1–4]. Whereas the level of adherence to HAART is… Expand
The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation
Getting HIV Under Control Approximately 1 in 300 people infected with HIV are HIV “controllers” who are able to maintain long-term control of the virus without medication and who do not progress to… Expand